97281-40-8

Basic information

• Product Name: Lysophosphatidylethanolamines, egg
• Synonyms: Lysophosphatidylethanolamines, egg;L-α-phosphatidylethanolaMine (Egg, Chicken);L-α-lysophosphatidylethanolamine (Egg, Chicken)
• CAS NO: 97281-40-8
• EINECS: 306-540-6
• Mol File: 97281-40-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Lysophosphatidylethanolamines, egg(CAS DataBase Reference)
• NIST Chemistry Reference: Lysophosphatidylethanolamines, egg(97281-40-8)
• EPA Substance Registry System: Lysophosphatidylethanolamines, egg(97281-40-8)

Safety Data

• Hazardous Substances Data: 97281-40-8(Hazardous Substances Data)

Usage

Description

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 and PD 98059 and the EGFR inhibitor AG-1478 . LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage. Lysophosphatidylethanolamines (egg) is a mixture of lysophosphatidylethanolamines isolated from chicken egg with fatty acyl groups of variable lengths at the sn-1 position and a hydroxy group at the sn-2 position.

Uses

Lysophosphatidyletha?nolamines, Egg is a natural Glycerophospholipid. Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.