97305-91-4Relevant academic research and scientific papers
Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes
Li, Xiaolan,Sun, Kai,Shen, Wenjuan,Zhang, Yong,Lu, Ming-Zhu,Luo, Xuzhong,Luo, Haiqing
, p. 31 - 36 (2021/01/09)
The stereoselective β-C(sp2)-H arylation of various acyclic enamides with arylsilanes via Rh(III)-catalyzed cross-coupling reaction was illustrated. The methodology was characterized by extraordinary efficacy and stereoselectivity, a wide scope of substrates, good functional group tolerance, and the adoption of environmentally friendly arylsilanes. The utility of this present method was evidenced by the gram-scale synthesis and further elaboration of the product. In addition, Rh(III)-catalyzed C-H activation is considered to be the critical step in the reaction mechanism.
N-Alkylation of some Secondary Styryl Enamides
Brettle, Roger,Shibib, Sa'ad M.,Wheeler, Kevin J.
, p. 831 - 836 (2007/10/02)
The preparation of some secondary styryl enamides of both the Z-and E-configuration, and their exclusively N-alkylation through their anions is described.Partial configurational inversion is observed under certain conditions during the alkylation of the d
