97315-39-4

Basic information

• Product Name: [4-(2-Chloro-ethoxy)-phenyl]-acetic acid ethyl ester
• CAS NO: 97315-39-4
• Molecular Weight: 242.702
• Mol File: 97315-39-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(2-Chloro-ethoxy)-phenyl]-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(2-Chloro-ethoxy)-phenyl]-acetic acid ethyl ester(97315-39-4)
• EPA Substance Registry System: [4-(2-Chloro-ethoxy)-phenyl]-acetic acid ethyl ester(97315-39-4)

Safety Data

• Hazardous Substances Data: 97315-39-4(Hazardous Substances Data)

Upstream product

• 80-41-1 2-chloroethyl tosylate 
• 17138-28-2 (4-hydroxy-phenyl)-acetic acid ethyl ester 

Downstream Products

• 97315-34-9 2-(4-(2-(1H-imidazol-1-yl)ethoxy)phenyl)acetic acid 

Relevant articles and documents

Selective Thromboxane Synthetase Inhibitors. 1. 1--1H-imidazoles

1-(2-Phenoxyethyl)-1H-imidazole was found to be an inhibitor of thromboxane (TxA2) synthetase, but it also inhibited the adrenal cytochrome P-450 enzyme steroid 11β-hydroxylase.The preparation of a series of analogues is described, and activity against TxA2 synthetase, PGI2 synthetase, cyclooxygenase, and steroid 11β-hydroxylase is discussed.Potency against TxA2 synthetase was increased by introduction of a carboxyl group at a suitable distance from the imidazole ring.A distance of 8.1-8.8 Angstroem between N-1 of the imidazole and the carboxyl carbon was found to be optimal.Introduction of a carboxyl group also had the effect of reducing activity against steroid 11β-hydroxylase.The most potent and selective compound was found to be 4-benzoic acid (14).