97347-23-4

Basic information

• Product Name: Butanoic acid, 2,4-bis[[(1,1-dimethylethoxy)carbonyl]amino]-, (4-nitrophenyl)methyl ester, (S)-
• CAS NO: 97347-23-4
• Molecular Formula: C21H31N3O8
• Molecular Weight: 453.492
• Mol File: 97347-23-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2,4-bis[[(1,1-dimethylethoxy)carbonyl]amino]-, (4-nitrophenyl)methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2,4-bis[[(1,1-dimethylethoxy)carbonyl]amino]-, (4-nitrophenyl)methyl ester, (S)-(97347-23-4)
• EPA Substance Registry System: Butanoic acid, 2,4-bis[[(1,1-dimethylethoxy)carbonyl]amino]-, (4-nitrophenyl)methyl ester, (S)-(97347-23-4)

Safety Data

• Hazardous Substances Data: 97347-23-4(Hazardous Substances Data)

Upstream product

• 619-73-8 4-nitrobenzyl chloride 
• 1482-98-0 (S)-2,4-diaminobutyric acid dihydrochloride 

Downstream Products

• 97347-33-6 Boc-Asn(Boc)-ONBzl 
• 97347-33-6 (R)-2,4-Bis-tert-butoxycarbonylamino-4-oxo-butyric acid 4-nitro-benzyl ester 

Relevant articles and documents

Chemical Conversion of L-α,ο-Diamino Acids to L-ο-Carbamoyl-α-amino Acids by Ruthenium tetroxide Oxidation

Ruthenium tetroxide oxidation of N,C-protected derivatives of L-2,4-diaminobutyric acid, L-ornitine and L-lisine was carried out two-phase conditions and the corresponding imides, formed through the oxidation of the methylene adjacent to the ο-amino group, were obtained in good yields.Removal of the protecting groups from the products gave L-asparagine, L-glutamine and L-2-aminoadipic acid 6-amide, respectively.Thus the first chemical conversion of L-α,ο-diamino acids into the corresponding L-ο-carbamoyl-α-amino acids without racemization has been established.L-2-Aminoadipic acid 6-amide was further converted to L-2-aminoadipic acid by acid hydrolysis.This represents a convenient method for the synthesis of L-2-aminoadipic acid starting from L-lisine.Keywords - oxidation; ruthenium tetroxide; L-α-amino acid synthesis; N-protecting group; ruthenium tetroxide; L-α,ο-diamino acid; L-ο-carbamoiyl-α-amino acid; L-2-aminoadipicacid