97364-45-9

Upstream product

• 100819-51-0 (1R,2S)-1-Benzoylamino-2-p-tolyl-cyclopropanecarboxylic acid methyl ester 
• 57427-88-0 (4E)-4-(4-methylbenzylidene)-2-phenyloxazol-5(4H)-one 
• 100819-51-0 (1R,2R)-1-Benzoylamino-2-p-tolyl-cyclopropanecarboxylic acid methyl ester 
• 97364-83-5 (1R,2S)-2-p-Tolyl-cyclopropane-1,1-dicarboxylic acid methyl ester 
• 39645-28-8 (1S,3S)-5-Phenyl-1-p-tolyl-6-oxa-4-aza-spiro[2.4]hept-4-en-7-one 
• 57427-79-9 (Z)-4-(4-methylbenzylidene)-2-phenyloxazol-5(4H)-one 
• 97364-34-6 (1S,2S)-1-Isocyanato-2-p-tolyl-cyclopropanecarboxylic acid methyl ester 
• 39645-28-8 (1R,3S)-5-Phenyl-1-p-tolyl-6-oxa-4-aza-spiro[2.4]hept-4-en-7-one 

Relevant academic research and scientific papers

Expanding the scope of donor/acceptor carbenes to N -phthalimido donor groups: Diastereoselective synthesis of 1-cyclopropane α-amino acids

Warming of 4-phthalimido-N-mesyl-1,2,3-triazole in the presence of alkenes followed by silica gel induced hydrolysis results in a highly diastereoselective and catalyst-free entry to N-phthalimidocyclopropanecarboxaldehydes.

SYNTHESIS OF E AND Z 1-AMINO-2-ARYL(ALKYL)-CYCLOPROPANECARBOXYLIC ACID via MELDRUM DERIVATIVES

The reaction of 5-arylidene(alkylidene)-2,2-dimethyl-1,3-dioxane-4,6-diones (1) (Meldrum's acid derivatives) with dimethylsulfoxonium methylide gave 1-aryl(alkyl)-6,6-dimethyl-4,8-dioxo-5,7-dioxaspiro octanes (2) which , on treatment with sodium meth