97387-48-9

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 97387-41-2 methyl 3-(2-aminophenyl)prop-2-ynoate 
• 97387-46-7 2-(1-Methyl-piperidin-4-ylidene)-propionic acid methyl ester 
• 97387-47-8 2-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)propanoic acid 
• 79655-46-2 (2-amino-phenyl)-propiolic acid 

Downstream Products

• 97387-49-0 {2-[2-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-propenylideneamino]-phenyl}-propynoic acid methyl ester 

Relevant academic research and scientific papers

A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity

α-Chloro-, bromo- and iodoenamines, which are readily prepared from the corresponding isobutyramides have been found to be excellent reagents for the transformation of a wide variety of alcohols or carboxylic acids into the corresponding halides. Yields are high and conditions are very mild thus allowing for the presence of sensitive functional groups. The reagents can be easily tuned allowing therefore the selective monohalogenation of polyhydroxylated molecules. The scope and chemoselectivity of the reactions have been studied and reaction mechanisms have been proposed.

INTRAMOLECULAR DIELS-ALDER CYCLOADDITIONS OF VINYLKETENIMINES. A CONVERGENT ROUTE TO CARBAZOLES AND PYRIDOCARBAZOLE ALKALOIDS

The intramolecular Diels-Alder cycloaddition of acetylenic vinylketenimines is the key step of a highly convergent synthesis of carbazoles.A facile synthesis of N-methyl-tetrahydroellipticine has been completed in five isolated steps from N-methyl piperidone.