97399-80-9

Usage

Type of compound

Complex chemical compound

Family

Derivative of the 7-methoxyisoflavone family

Molecular structure

Contains a benzofuran ring
Features a 3-hydroxy-1-propenyl side chain
Multiple hydroxyl and methoxy groups
1,3-propanediol moiety
Potential biological activity
Potential pharmaceutical relevance
Further research needed for full understanding of properties and applications

Upstream product

• 458-35-5 coniferol 
• 20675-96-1 Syringenin 
• 97399-78-5 buddlenol A 

Relevant academic research and scientific papers

Enantiomeric neolignans and sesquineolignans from Jatropha integerrima and their absolute configurations

Two pairs of new sesquineolignan enantiomers, (±)-jatrointelignans A and B (1a/1b and 2a/2b), one pair of new neolignan enantiomers, (±)-jatrointelignan D (4a/4b), and two new neolignans, (+)-jatrointelignan C (3a), and (+)-schisphenlignan I (5a) together

Arabidopsis peroxidase-catalyzed copolymerization of coniferyl and sinapyl alcohols: Kinetics of an endwise process

In order to determine the mechanism of the earlier copolymerization steps of two main lignin precursors, sinapyl (S) alcohol and coniferyl (G) alcohol, microscale in vitro oxidations were carried out with a PRX34 Arabidopsis thaliana peroxidase in the presence of H2O2. This plant peroxidase was found to have an in vitro polymerization activity similar to the commonly used horseradish peroxidase. The selected polymerization conditions lead to a bulk polymerization mechanism when G alcohol was the only phenolic substrate available. In the same conditions, the presence of S alcohol at a 50/50 S/G molar ratio turned this bulk mechanism into an endwise one. A kinetics monitoring (size-exclusion chromatography and liquid chromatography-mass spectrometry) of the different species formed during the first 24 h oxidation of the S/G mixture allowed sequencing the bondings responsible for oligomerization. Whereas G homodimers and GS heterodimers exhibit low reactivity, the SS pinoresinol structure act as a nucleating site of the polymerization through an endwise process. This study is particularly relevant to understand the impact of S units on lignin structure in plants and to identify the key step at which this structure is programmed.