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Ungeremine, also known as 2-(4-methoxyphenyl)-N-[2-(1-pyrrolidinyl)ethyl]ethanamine, is a synthetic chemical compound that belongs to the class of phenethylamine derivatives. It is primarily recognized for its psychoactive properties and has been studied for its potential effects on the central nervous system. Ungeremine is structurally similar to certain psychoactive substances, and its chemical structure is characterized by a phenethylamine backbone with a 4-methoxyphenyl group and a pyrrolidinylethyl side chain. Due to its complex nature and potential for misuse, ungeremine is not approved for medical use and is subject to regulatory controls in many countries. It is important to note that the compound's effects and safety profile are not well-established, and it should be approached with caution due to the lack of comprehensive research and potential health risks.

97438-92-1

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97438-92-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 97438-92-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,4,3 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 97438-92:
(7*9)+(6*7)+(5*4)+(4*3)+(3*8)+(2*9)+(1*2)=181
181 % 10 = 1
So 97438-92-1 is a valid CAS Registry Number.

97438-92-1Downstream Products

97438-92-1Relevant articles and documents

Total synthesis of the amaryllidaceae alkaloid ungeremine

Lauk, Urs,Duerst, Doris,Fischer, Walter

, p. 65 - 68 (1991)

The synthesis of the aromatic Amaryllidaceae alkaloid ungeremine 1 with a new type of radical cyclisation as the key step is reported.

Ungeremine and its hemisynthesized analogues as bactericides against flavobacterium columnare

Schrader, Kevin K.,Avolio, Fabiana,Andolfi, Anna,Cimmino, Alessio,Evidente, Antonio

, p. 1179 - 1183 (2013/04/10)

The Gram-negative bacterium Flavobacterium columnare is the cause of columnaris disease, which can occur in channel catfish (Ictalurus punctatus). In a previous study, the betaine-type alkaloid ungeremine, 1, obtained from Pancratium maritimum L. was found to have strong antibacterial activity against F. columnare. In this study, analogues of 1 were evaluated using a rapid bioassay for activity against F. columnare to determine if the analogues might provide greater antibacterial activity and to determine structure-activity relationships of the test compounds. Several ungeremine analogues were prepared by hydrochlorination of the alkaloid and by selenium dioxide oxidation of both lycorine, 7, and pseudolycorine, 8, which yielded the isomer of ungeremine, 3, and zefbetaine, 4, respectively. The treatment of lycorine with phosphorus oxychloride allowed the synthesis of an anhydrolycorine lactam, 5, showing, with respect to 1, the deoxygenation and oxygenation of C-2 and C-7 of the C and B rings, respectively. The results of the structure-activity relationship studies showed that the aromatization of the C ring and the oxidation to an azomethine group of C-7 of the B ring are structural features important for antibacterial activity. In addition, the position of the oxygenation of the C ring as well as the presence of the 1,3-dioxole ring joined to the A ring of the pyrrolo[de]phenanthridine skeleton also plays a significant role in imparting antibacterial activity. On the basis of 24-h 50% inhibition concentration (IC50) results, ungeremine hydrochloride, 2, was similar in toxicity to 1, whereas 5 had the lowest activity. Analogue 2 is soluble in water, which may provide the benefit for use as an effective feed additive or therapeutant compared to ungeremine.

Concise syntheses of the amaryllidaceae alkaloids ungerimine and hippadine via the suzuki aryl-aryl cross coupling reaction

Siddiqui,Snieckus

, p. 1523 - 1526 (2007/10/02)

Short syntheses of the betaine alkaloid ungerimine (1) and the lactam alkaloid hippadine (4) based on aryl boronic acid - aryl halide cross coupling methodology are described.

OCCURRENCE OF TWO EPIMERIC ALKALOIDS AND METABOLISM COMPARED WITH LYCORINE IN CRINUM LATIFOLIUM

Ghosal, Shibnath,Unnikrishnan, Sankara,Singh, Sushil K.

, p. 2535 - 2537 (2007/10/02)

Two new epimeric pyrrolophenanthridine alkaloids, 2-epilyocorine and 2-epipancrassidine, were isolated from the flower-stem fluid of Crinum latifolium.The structures of the two alkaloids were established by spectroscopic analyses, crucial chemical transformation, and synthesis in case of the former.The differences in the metabolic pathways of lycorine and 2-epilycorine were studied under simulated physiological conditions and their biochemical significance was appraised.Key Word Index - Crinum latifolium; Amaryllidaceae; epimeric alkaloids; 2-epilycorine; 2-epipancrassidine, metabolic pathways; biochemical significance.

ALKALOIDS OF ZEPHYRANTHES FLAVA

Ghosal, Sibnath,Singh, Sushil K.,Srivastava, Radhey S.

, p. 1975 - 1978 (2007/10/02)

From fresh, mature seeds of Zephyranthes flava, two new 2-oxyphenanthridinium alkaloids, zefbetaine and zeflabetaine along with 15 known free and glucosyloxy alkaloids have been isolated by gradient solvent extraction, chromatography and derivatization.The new compounds have been characterized by comprehensive spectroscopic analyses, chemical transformations and synthesis.Additionally, changes in the major alkaloids during development of the fruits have been analysed and their biological significance appraised.

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