97475-96-2Relevant articles and documents
Flow microwave technology and microreactors in synthesis
Baxendale, Ian R.,Hornung, Christian,Ley, Steven V.,De Mata Munoz Molina, Juan,Wikstroem, Anders
, p. 131 - 144 (2013/03/28)
A bespoke microwave reactor with a glass containment cell has been developed for performing continuous flow reactions under microwave heating. The prototype unit has been evaluated using a series of standard organic chemical transformations enabling scale-up of these chemical processes. As part of the development, a carbon-doped PTFE reactor insert was utilized to allow the heating of poorly absorbing reaction media, increasing the range of solvents and scope of reactions that can be performed in the device.
Cis,endo-2-azabicycloalkane-3-carboxylic acid derivatives, their use and intermediates in their preparation
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, (2008/06/13)
The invention relates to compounds of the formula I STR1 in which n is 1, 2 or 3, Z1 and Z2, and Z3 and Z4, in each case together represent a chemical bond or Z1, Z2, Z3 and Zsu
Angiotensin-converting enzyme inhibitors
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, (2008/06/13)
Novel compounds with angiotensin-converting enzyme inhibitory activity are disclosed. Such compounds are useful in the treatment of cardiovascular disorders, especially hypertension and congestive heart failure, and are useful in the treatment of glaucoma
EINE EINFACHE DIASTEREOSELEKTIVE SYNTHESE VON (1SR,3SR,5SR)-2-AZABICYCLOOCTAN-3-CARBONSAEURE
Urbach, H.,Henning, R.
, p. 1839 - 1842 (2007/10/02)
(1SR,3SR,5SR)-2-Azabicyclooctane-3-carboxylic acid, precursor of the angiotensin-converting-enzyme-inhibitor Hoe 498, is easily prepared from 1-chloro-1-cyclopentene-2-carbaldehyde in three steps.