97482-27-4

Basic information

• Product Name: 1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-3,3-dimethyl-,(S)-(9CI)
• Synonyms: 1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-3,3-dimethyl-,(S)-(9CI)
• CAS NO: 97482-27-4
• Molecular Formula: C₈H₁₄N₂O
• Molecular Weight: 0
• Product Categories: PYRROLE
• Mol File: 97482-27-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-3,3-dimethyl-,(S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-3,3-dimethyl-,(S)-(9CI)(97482-27-4)
• EPA Substance Registry System: 1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-3,3-dimethyl-,(S)-(9CI)(97482-27-4)

Safety Data

• Hazardous Substances Data: 97482-27-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrrolo[1,2-c]imidazol-1-one, hexahydro-3,3-dimethyl-,(S)-(9CI) is used as a building block in organic synthesis for the production of various biologically active molecules. Its chiral nature and unique structure make it a valuable component in the development of new drugs and pharmaceuticals.
Used in Medicinal Chemistry:
1H-Pyrrolo[1,2-c]imidazol-1-one, hexahydro-3,3-dimethyl-,(S)-(9CI) is used in medicinal chemistry for its potential biological activities and pharmacological properties. Researchers are interested in exploring its applications in drug development due to its unique chemical structure and properties.
Used in Drug Development:
1H-Pyrrolo[1,2-c]imidazol-1-one, hexahydro-3,3-dimethyl-,(S)-(9CI) is used in drug development to create new and innovative pharmaceuticals. Its potential biological activities and pharmacological properties make it a promising candidate for the development of novel therapeutic agents.

Upstream product

• 67-64-1 acetone 
• 7531-52-4 L-prolinamide 

Downstream Products

• 174089-62-4 (2S)-N-propan-2-ylpyrrolidine-2-carboxamide 
• 7531-52-4 L-prolinamide 
• 185736-59-8 (4R,5S,6S)-3-[2-((S)-3,3-Dimethyl-1-oxo-tetrahydro-pyrrolo[1,2-c]imidazol-2-yl)-ethylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 185736-39-4 (5S)-2,2-dimethyl-3-(2-p-toluenesulfonyloxyethyl)-1,3-diazabicyclo[3.3.0]octan-4-one 

Relevant articles and documents

The role of Zn2+ in enhancing the rate and stereoselectivity of the aldol reactions catalyzed by the simple prolinamide model

The aldol reaction between acetone and 4-nitrobenzaldehyde catalyzed by single l-prolinamide and its zinc complexes has been studied. An increase in the rate and the stereoselectivity of the reaction has been shown by using zinc derivatives. A mechanistic

Inhibition of imidazolidinone intermediate formation in the aldol reactions catalyzed by zinc-prolinamide complexes

The use of zinc salts as cocatalysts in aldol condensations catalyzed by single prolinamide (and in the extension by other more complex prolinamides) can prevent the formation of the parasitic intermediate imidazolidinone, with faster and also more stereoselective reactions than those catalyzed by the free amine. This new finding, together with this ion's already known properties, make zinc salts highly suitable additives for aldol reactions catalyzed for prolinamide derivatives.

Synthesis and antibacterial activity of 1-β-methylcarbapenem having a 1,3-diazabicyclo[3.3.0]octan-4-one moiety

The synthesis of new series of 1-β-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octan-4-one moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram negative bacteria are reported and the effect of the substituent on the bicyclic ring was investigated and was in agreement with findings from our previous studies.

OPTICAL ACTIVITY OF LACTONES AND LACTAMS-IV CHIROPTICAL PROPERTIES OF 4-IMIDAZOLIDINONES

The chiroptical properties of 4-imidazolidinones are reviewed.Several optically active compounds were obtained from amides and N-methylamides of corresponding N-acylamino acids.The origin of the two lowest energy electronic transitions is considered.The e