97511-21-2Relevant articles and documents
CATALYZED LIQUID-PHASE OXIDATION OF DIALKYLTHIOPHENES
Volkov, M. N.,Kazakova, O. A.
, p. 553 - 557 (1981)
The oxidation of 3-methyl-2-ethylthiophene with molecular oxygen in glacial acetic acid in the presence of cobalt-bromide catalyst was investigated.It was established that there is a dependence of the rate of oxidation of this compound on its concentration, on the catalyst (cobalt acetate) concentration, and on the initiator (NaBr) concentration.The principal oxidation products are 3-methyl-2-acetothienone (III) and 1-(3-methyl-2-thienyl)ethyl acetate, which were isolated and characterized.The reactivity of 3-methyl-2-ethylthiophene in the oxidation reaction is higher than that of 4-methyl-2-ethylthiophene.
A highly active ytterbium(III) methide complex for truly catalytic Friedel-Crafts acylation reactions
Barrett, Anthony G. M.,Bouloc, Nathalie,Braddock, D. Christopher,Chadwick, David,Henderson, David A.
, p. 1653 - 1656 (2007/10/03)
The Friedel-Crafts acylation of anisole with acetic anhydride using ytterbium(III) tri[tris(nonafluorobutanesulfonyl)methide] was studied with respect to catalyst loading. A strong inhibitory effect due to the product became apparent from doping experiments and from examination of the kinetic data. This understanding allowed catalyst loadings to be reduced to as little as 0.1 mol% for effective acylation under a suitable temperature and pressure regime.
Kinetics of the Detritiation of a Series of 4- and 5-Substituted 2-(acetyl)thiophenes
Jones, John R.,Pearson, Gerd M.,Spinelli, Domenico,Consiglio, Giovanni,Arnone, Caterina
, p. 557 - 558 (2007/10/02)
A series of 4- and 5-substituted 2-(acetyl)thiophenes have been prepared and the kinetics of the hydroxide-catalysed detritiation studied at 25.0 deg C.The second-order detritiation rate constants parallel those observed for the corresponding meta- and para-substituted acetophenones but as the reaction constant ρ is higher (1.61) the range of reactivity is much wider than that witnessed for the acetophenones.