97512-72-6

Upstream product

• 186581-53-3 diazomethane 
• 97510-44-6 (Z)-Boc-Phe-ΔPhe 
• 67-56-1 methanol 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 74805-42-8 N-carboxy-α-dehydrophenylalanine anhydride 
• 591-50-4 iodobenzene 
• 79807-13-9 methyl 2-({(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl}-amino)-acrylate 
• 34290-59-0 (S)-methyl 2-((2S)-2-[(tert-butoxycarbonyl)-3-phenylpropanamido]-3-hydroxy)-propanoate 
• 110697-93-3 Boc-Phe-Phe-azlactone 

Downstream Products

• 1242683-71-1 Boc-L-Phe-E-ΔPhe(β-Br)-OMe 
• 1242683-42-6 Boc-L-Phe-Z-ΔPhe(β-Br)-OMe 
• 1242683-57-3 Boc-L-Phe-Z-ΔPhe(β-I)-OMe 

Relevant academic research and scientific papers

Pd(0)-catalyzed Heck-type arylation of didehydropeptides

Pd(0)-catalyzed Heck-type arylation of several didehydropeptides has been studied and the process has been found to be a viable method for the synthesis of the corresponding arylated products stereoselectively but in moderate yields. Copyright Taylor & Fr

Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-α,β-didehydrophenylalanine (δZPhe) residues

New endomorphin-2 (EM-2) analogues incorporating (Z)-α,β- didehydrophenylalanine (δZPhe) in place of the native phenylalanine in EM-2 are reported. Tyr-Pro-δZPhe-Phe-NH 2 {[δZPhe3]EM-2} (1), Tyr-Pro-P

SYNTHESIS OF PEPTIDES WITH α,β-DEHYDROAMINO ACIDS. PART VIII. A CONVENIENT SYNTHESIS OF N-PROTECTED α,β-DEHYDROPEPTIDE METHYL ESTERS

Based on results of the examination of the action of diazomethane on Z-Gly-ΔAbu and/or Z-Gly-ΔAbu-OMe (Table 1) a series of twelve model N-protected α,β-dehydrodipeptide methyl esters 1-12 was obtained.Yields and purity of isolated products amounted to 80-94percent and 98-100percent, respectively (Table 2).

Dehydrooligopeptides. VII. Convenient Synthesis of Various Dehydrodi- and tripeptide Esters by Using N-Carboxy α-Dehydroamino Acid Anhydride

The one-pot syntheses of N-protected Δ1- and Δ2-dehydrodipeptide esters by the coupling of N-carboxy α-dehydroamino acid anhydride (ΔNCA) with several kinds of C- or N-protected L-α-amino acids are described.In addition, it was found that a similar coupling of ΔNCA with both C- and N-protected α-amino acids also took place to give Δ2-dehydrotripeptide derivatives, involving eight kinds of important C-terminal segments of antrimycins and cirratiomycins.The configurational confirmation of the α-dehydroisoleucine residue of the antibiotics is also discussed.