97533-36-3Relevant academic research and scientific papers
Synthesis of new oxazole-containing peptidomimetics
Falorni, Massimo,Dettori, Giovanna,Giacomelli, Giampaolo
, p. 1419 - 1426 (2007/10/03)
Enantiospecific syntheses of optically active amino acids containing an oxazole moiety are described. Two different strategies for their insertion in a peptidomimetic chain are also discussed. The procedures presented are based on materials readily available in multigram quantities.
A Simple Method for Amide Formation from Protected Amino Acids and Peptides
Chen, Shui-Tein,Wu, Shih-Hsiung,Wang, Kung-Tsung
, p. 37 - 38 (2007/10/02)
Amide formation from protected amino acids and peptides is directly and simply achieved by using 1-hydroxybenzotriazole as activating agent and treating the intermediate O-(benzotriazol-1-yl) derivative ("active ester") in situ with 25percent ammonium hydroxide solution.
THE PREPARATION AND REACTIONS OF MIXED ANHYDRIDES OF N-ALKOXYCARBONYLAMINO ACIDS
Chen, Francis M. F.,Benoiton, N. Leo
, p. 619 - 625 (2007/10/02)
Pure mixed anhydrides R1OCO-Xxx-O-COOR2 (Xxx=NHCHRCO) have been obtained by reaction of N-alkoxycarbonylamino acids R1OCO-Xxx-OH with alkyl chloroformate R2OCOCl (R2=methyl, ethyl, isobutyl, menthyl)
