97551-20-7Relevant articles and documents
Synthesis of Chiral Alkenyl Cyclopropane Amino Acids for Incorporation into Stapled Peptides
Yuen, Tsz Ying,Brown, Christopher J.,Tan, Yaw Sing,Johannes, Charles W.
, p. 1556 - 1566 (2020/01/22)
α,α′-Disubstituted amino acids serve as important non-proteinogenic amino acids in the construction of stabilized helical peptides. To expand the repertoire of α,α′-disubstituted amino acids, chiral alkenyl-containing cyclopropane amino acids were synthes
Metallophosphites as Umpolung Catalysts: The Enantioselective Cross Silyl Benzoin Reaction
Linghu, Xin,Potnick, Justin R.,Johnson, Jeffrey S.
, p. 3070 - 3071 (2007/10/03)
Carbonyl polarity reversal (umpolung) has been realized employing metallophosphites as catalysts. As a result, nonenzymatic asymmetric cross silyl benzoin reactions have been achieved, giving optically active silyl ether-protected benzoin adducts. The reaction is general with respect to aryl, alkyl, and heterocyclic substrates with good to excellent yields and good to excellent enantioselectivities. Copyright
Asymmetric synthesis of substituted 1-aminocyclopropane-1-carboxylic acids from a new chiral glycine equivalent with 3,6-dihydro-2H-1,4-oxazin-2- one structure
Chinchilla, Rafael,Falvello, Larry R.,Galindo, Nuria,Najera, Carmen
, p. 2223 - 2227 (2007/10/03)
Condensation of the new chiral glycine equivalent 10 with aldehydes at room temperature in the presence of K2CO3 under solid-liquid phase- transfer-catalysed conditions afforded stereoselectively new chiral (Z)- α,β-didehydroamino ac
