97561-04-1

Upstream product

• 42245-42-1 methyl 3-(4-methoxyphenyl)glycidate 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 5703-26-4 4-Methoxyphenylacetaldehyde 
• 5958-02-1 3-(4-methoxyphenyl)pyridine 
• 190377-15-2 4-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-ylamine 
• 106044-85-3 (2R,3S)-trans-(4-methoxyphenyl)glycidic acid ethyl ester 
• 105560-93-8 methyl (2R,3S)-3-(4-methoxyphenyl)glycidate 
• 136597-65-4 (-)-(2R,3S)-sodium 3-(4-methoxyphenyl)glycidate 

Relevant academic research and scientific papers

Efficient Preparation of Alkaloids Polycarpine and Polycarpaurines A and C

An efficient method for the preparation of alkaloids polycarpine and polycarpaurines A and C via microwave-assisted three-step one-pot reaction as the key step has been developed. This is the first report about the synthesis of polycarpaurines A and C. Starting from commercially available p-methoxybenzaldehyde, polycarpine and polycarpaurine A were obtained over seven steps with 40 and 24 % overall yield, respectively. Polycarpine could convert to polycarpaurine C in 72% yield in the presence of NaHSO3. The structure of polycarpine and polycarpaurines A and C was confirmed by1H NMR,13C NMR, and HRMS.

Synthesis of 3-Arylpyridines via Palladium/Copper-Catalyzed Annulation of Allylamine/1,3-Propanediamine and Aldehydes

A novel and efficient method for the synthesis of 3-arylpyridines from allylamine/propanediamine and aldehydes by palladium/copper-catalyzed oxidative tandem cyclization has been developed. With this reaction, a series of desired 3-arylpyridines was synthesized in moderate yields via C-C/C-N bond formation and 6-endo/exo-trig cyclization.