97571-08-9Relevant academic research and scientific papers
Pd-Catalyzed Conjunctive Cross-Coupling between Grignard-Derived Boron “Ate” Complexes and C(sp2) Halides or Triflates: NaOTf as a Grignard Activator and Halide Scavenger
Lovinger, Gabriel J.,Aparece, Mark D.,Morken, James P.
, p. 3153 - 3160 (2017)
Catalytic enantioselective conjunctive cross-couplings that employ Grignard reagents are shown to furnish an array of nonracemic chiral organoboronic esters in an efficient and highly selective fashion. The utility of sodium triflate in facilitating this reaction is two-fold: it enables “ate” complex formation and overcomes catalytic inhibition by halide ions.
An α-lithio boronic ester from an α-trimethylstannyl boronic ester
Matteson, Donald S.,Wilson, John W.
, p. 1690 - 1692 (2008/10/08)
Pinacol (1-chloroethyl)boronate (1A) and lithiotrimethylstannane have yielded pinacol [1-(trimethylstannyl)ethyl]boronate (2), which with methyllithium at -100C yields pinacol 1-lithioethylboronate (3). Capture of 3 by (-haloalkyl)boronic esters results in carbon-carbon bond formation. Generation of 3 from pinacol (1-iodoethyl)boronate with tert-butyllithium is followed by rapid reaction with the remaining (1-iodoethyl)boronate.
