97579-34-5Relevant academic research and scientific papers
COMPOUNDS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES
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Page/Page column 64, (2016/05/02)
The present invention relates to compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
Practical one-pot sequence for the asymmetric synthesis of 1,2 diols from primary alcohols
Hermange, Philippe,Portalier, Fran?ois,Thomassigny, Christine,Greck, Christine
supporting information, p. 1052 - 1055 (2013/04/10)
A practical one-pot three-step sequence is reported for the asymmetric synthesis of α-benzoyloxylated alcohols from primary alcohols. Good overall yields (36-52%) and enantioselectivities (91-94% e.e.) are obtained using a commercial organocatalyst in the key oxylation reaction. A simple modification in the protocol allows the formation of enantioenriched γ-benzoyloxylated α,β-unsaturated ester from alcohol. Synthetic utility has been harnessed to the easy preparation of (-)-γ-octalactone from hexan-1-ol.
A practical synthesis of (R)- and (S)-(E)-4-hydroxyalk-2-enals, cytotoxic products of the microsomal lipid peroxidation
Allevi,Anastasia,Ciuffreda,Sanvito
, p. 927 - 934 (2007/10/02)
The chemical synthesis of some (S)- and (R)-(E)-4-hydroxyalk-2-enals, important products of lipid peroxidation (LPO), has been carried out via enantiomerically pure 2-benzoyloxyaldehydes, chiral key intermediates obtained from two diastereomeric diepoxide
