97589-07-6Relevant academic research and scientific papers
A General Strategy for the Total Synthesis of the Presumed Lipoxin Structures
Nicolaou, K. C.,Webber, S. E.
, p. 297 - 299 (1985)
Stereocontrolled total syntheses of four possible isomers of lipoxin B by a Pd(0)-Cu(I) catalysed coupling reaction as a key step are described.
A versatile route to conjugated hydroxy (E,Z,E,E)-tetraenoic acids: Highly chemo- and stereoselective synthesis of lipoxin B4
Alami, Mouad,Crousse, Benoit,Linstrumelle, Gerard,Mambu, Lengo,Larcheveque, Marc
, p. 2949 - 2958 (2007/10/03)
A highly convergent total stereocontrolled synthesis of lipoxin B4 is described by an efficient Pd-catalyzed coupling reaction of two easily accessible chiral synthons 2 and 3 without any protection-deprotection sequence of the alcohol function
Stereocontrolled Total Synthesis of Lipoxins B
Nicolaou, K. C.,Webber, S. E.
, p. 453 - 461 (2007/10/02)
A stereocontrolled total synthesis of six lipoxin B isomers are described.The flexible and stereoselective strategy involves Sharpless asymmetric epoxidation and pinylborane asymmetric reduction to secure the three hydroxyl-bearing stereocenters and a Wittig-type as well as palladium(0)-copper(I) coupling reactions to construct the carbon skeleton of the target molecules.
SYNTHESIS OF LIPOXIN B
Morris, Joel,Wishka, Donn G.
, p. 803 - 806 (2007/10/02)
The synthesis of four isomers of 5,14,15-triHETE is reported.The key step is the coupling of acetylene 11 (or 19) with epoxide 7 to afford alcohol 12 (or 20).Natural lipoxin B is found to correspond to a mixture of 14R-8-cis-1 14R-8-trans-3 and 14S-8-tran
ON THE SYNTHESIS AND STRUCTURE OF LIPOXIN B
Corey, E. J.,Mehrotra, Mukund M.,Su, Wei-guo
, p. 1919 - 1922 (2007/10/02)
A synthesis of lipoxin B, a recently discovered biologically active eicosanoid, and the assignment of stereoformula 2 is reported.
