78606-79-8

Upstream product

• 76745-18-1 (+)-(S,R)-δ-hydroxyoxiranepentanoic acid methyl ester 
• 98-88-4 benzoyl chloride 
• 78606-78-7 methyl (E,5S,6R)-5,6,7-trihydroxyhept-2-enoate 
• 76745-16-9 4-[(4S,5R)-2,2-Dimethyl-5-(toluene-4-sulfonyloxymethyl)-[1,3]dioxolan-4-yl]-butyric acid methyl ester 
• 22900-10-3 2-deoxy-D-ribose 
• 533-67-5 2-Deoxy-D-ribose 
• 78606-80-1 5(S), 6(R), 7-trihydroxyheptanoic acid methyl ester 
• 76745-17-0 (5S,6R)-5,6-Dihydroxy-7-(toluene-4-sulfonyloxy)-heptanoic acid methyl ester 
• 76745-15-8 4-((4S,5R)-5-Hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester 
• 86795-44-0 3,4-O-isopropylidene-2-deoxy-D-ribose 

Downstream Products

• 105470-57-3 Benzoic acid (6E,8E)-(1S,2R)-9-((4S,5S)-2,2-dimethyl-5-pentyl-[1,3]dioxolan-4-yl)-2-hydroxy-1-(3-methoxycarbonyl-propyl)-nona-6,8-dien-4-ynyl ester 
• 105448-69-9 Benzoic acid (6E,8E)-(1S,2R,10R,11S)-10,11-bis-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-1-(3-methoxycarbonyl-propyl)-hexadeca-6,8-dien-4-ynyl ester 
• 76745-20-5 Methyl 5S-benzoyloxy-5-formylvalerate 
• 76745-19-2 (5S,6R)-Methyl 5-(benzyloxy)-6,7-dihydroxyheptanoate 
• 78606-81-2 Benzoic acid (2Z,5Z)-(S)-1-(3-methoxycarbonyl-propyl)-6-[(2R,3R)-((Z)-3-oct-2-enyl)-oxiranyl]-hexa-2,5-dienyl ester 
• 105448-75-7 Benzoic acid (2E,6E,8E)-(S)-9-((4S,5S)-2,2-dimethyl-5-pentyl-[1,3]dioxolan-4-yl)-1-(3-methoxycarbonyl-propyl)-nona-2,6,8-trien-4-ynyl ester 
• 97589-07-6 5S,14R,15S-6,10,12-trans-8-cis-triHETE methyl ester 
• 105499-57-8 Benzoic acid (2E,4Z,6E,8E)-(1S,10S,11S)-10,11-dihydroxy-1-(3-methoxycarbonyl-propyl)-hexadeca-2,4,6,8-tetraenyl ester 
• 105500-39-8 Benzoic acid (2E,4Z,6E,8E)-(1S,10R,11S)-10,11-dihydroxy-1-(3-methoxycarbonyl-propyl)-hexadeca-2,4,6,8-tetraenyl ester 
• 105448-71-3 Benzoic acid (2E,6E,8E)-(1S,10S,11S)-10,11-dihydroxy-1-(3-methoxycarbonyl-propyl)-hexadeca-2,6,8-trien-4-ynyl ester 
• 105448-71-3 Benzoic acid (2E,6E,8E)-(1S,10R,11S)-10,11-dihydroxy-1-(3-methoxycarbonyl-propyl)-hexadeca-2,6,8-trien-4-ynyl ester 
• 102906-17-2 Benzoic acid (2Z,6E,8E)-(1S,10R,11S)-10,11-bis-(tert-butyl-dimethyl-silanyloxy)-1-(3-methoxycarbonyl-propyl)-hexadeca-2,6,8-trien-4-ynyl ester 
• 103001-18-9 Benzoic acid (2E,6E,8E)-(1S,10R,11S)-10,11-bis-(tert-butyl-dimethyl-silanyloxy)-1-(3-methoxycarbonyl-propyl)-hexadeca-2,6,8-trien-4-ynyl ester 
• 76745-31-8 methyl 5(S)-(benzoyloxy)-12(R)-hydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 

Relevant academic research and scientific papers

SYNTHESIS OF LIPOXIN B

The synthesis of four isomers of 5,14,15-triHETE is reported.The key step is the coupling of acetylene 11 (or 19) with epoxide 7 to afford alcohol 12 (or 20).Natural lipoxin B is found to correspond to a mixture of 14R-8-cis-1 14R-8-trans-3 and 14S-8-tran

A STEREOCONTROLLED AND EFFECTIVE SYNTHESIS OF LEUKOTRIENE B (1).

An efficient synthesis of leukotriene B (1) is reported which renders this important substance accessible in quantity.The process is convergent and includes a novel method for stereospecific generation of the conjugated triene unit.