97590-64-2Relevant academic research and scientific papers
First stereoselective synthesis of (4aS,5R)-4,4a,5,6,7,8-hexahydro-4a,5- dimethyl-2(3H)-naphthalenone
Cuesta, Xavier,Gonzalez, Asensio,Bonjoch, Josep
, p. 3365 - 3370 (1999)
The synthesis of enantiomerically pure (4aS,5R)-hexahydro-4a,5-dimethyl- 2(3H)-naphthalenone (-)-1 is described for the first time. The synthesis starts from (R)-3-methylcyclohexanone and involves the preparation of Piers enol lactone 6 in its enantiopure
REGIOSELECTIVE SYNTHESIS OF OPTICALLY ACTIVE (R)-5-METHYL- AND (R)-7-METHYL-5,6,7,8-TETRAHYDROQUINOLINES
Chelucci, Giorgio,Cossu, Sergio,Scano, Gianfranco,Soccolini, Francesco
, p. 1397 - 1403 (2007/10/02)
Five synthesis routes have been evaluated for the regioselective preparation of (R)-5-methyl- and (R)-7-methyl-5,6,7,8-tetrahydroquinolines from (+)-(R)-3-methylcyclohexanone.
Optical Rotatory Dispersion Studies. 138. Synthesis and Conformational Analysis of β-Heteroatom-Substituted Cyclohexanones
Gorthey, Lee Ann,Vairamani, Mariappandar,Djerassi, Carl
, p. 4173 - 4182 (2007/10/02)
Circular dichroism and proton magnetic resonance spectroscopy were used in the conformational analysis of a series of β-heteroatom-substituted cyclohexanones.It was found that the axial population of the substituted ketone relative to that of the monosubstituted cyclohexanone is enhanced for the more highly electronegative substituents oxygen and fluorine and decreased for the less electronegative substituents chlorine, bromine, and sulfur.Possible mechanisms underlying this behavior, including electrostatic and dipole-dipole interactions as well as through-space and through-bond orbital interactions, are briefly discussed.
Conformational Studies of R-(+)-2-Alkylidene- and R-(-)-2-Benzylidene-5-methylcyclohexanones
Anand, Devinder K.,Hargreaves, Michael K.,Khan, Mohsin A.
, p. 978 - 988 (2007/10/02)
The cis and trans 2-alkylidene-5-methylcyclohexanones have been separated and distinguished. 2-Benzylidene-5-methylcyclohexanone was also prepared in both forms.The CD, ORD, UV and IR spectra are recorded and discussed.The NMR data include solvent and tem
