97600-49-2Relevant articles and documents
N -Alkyl calix[4]azacrowns for the selective extraction of uranium
Wehbie, Moheddine,Arrachart, Guilhem,Le Goff, Xavier F.,Karamé, Iyad,Pellet-Rostaing, Stéphane
, p. 14594 - 14603 (2018)
The selective extraction of uranium by N-octylcalix[4]azacrown (NOCAC) and N-ethylhexylcalix[4]azacrown (NEHCAC) was investigated. The ligands were synthesised in three steps through the functionalisation of t-butyl calix[4]arene at the distal-1,3-positions of the lower rim with ethyl acetate groups followed by cyclisation with (imino)bis(ethane-2,1-diyl)diamide. A detailed investigation on the effect of various parameters, such as the aqueous phase acidity (sulfuric acid), the ionic strength, and ligand concentration, on the extraction of uranium(vi) has been conducted. The effect of the H2SO4 concentration has been studied from 0.02 to 3 M. Preliminary studies carried out on NOCAC in dodecane/octanol diluents showed that the uranium extraction from sulfuric acid is more efficient at a low H2SO4 concentrations. The stoichiometry of complexation was estimated from the slope method, NMR titration, and electrospray ionisation-mass spectrometry analysis. Both ligands were found to be highly selective for uranium(vi) over other competitive cations present in a simulated leach solution containing seven competitive cations. The successful recovery of the uranium from the organic phase has been performed thanks to stripping steps involving ammonium oxalate, ammonium carbonate, and sodium carbonate as stripping agents.
Non-trivial solution chemistry between amido-pyridylcalix[4]arenes and some metal salts
Colleran, John J.,Creaven, Bernadette S.,Donlon, Denis F.,McGinley, John
, p. 10928 - 10936 (2010)
Mercury ion complexation reactions were carried out between 3 and various mercury(ii) salts. 1H NMR studies showed that the role of solvent, the anion chosen and the initial reaction conditions were critical and that the formation of a "simple" mercury(ii) complex was non-trivial. The mercury(ii) ion can cause either (i) the formation of an ion-pair system, which have a characteristic doubling of all signals in the 1H NMR spectrum, (ii) a cleavage reaction to occur resulting in the reformation of the calix[4]arene diester compound 2, but only when the reaction is heated and (iii) "simple" mercury binding to the pyridine rings when the binding studies are carried out using NMR titration techniques. The electrochemistry results, on the same systems, show that the initial reaction involves the removal of the phenoxide protons followed by the resulting catalysis of the mercury species. This proton removal is not observed in the NMR spectra of any of the mercury reactions. It was also found that 3 could bind silver and zinc salts and was not selective for mercury(ii) as was previously described. The Royal Society of Chemistry 2010.
Synthesis, biological evaluation and molecular docking of calix[4]arene-based β-diketo derivatives as HIV-1 integrase inhibitors
Luo, Zaigang,Zhao, Yu,Ma, Chao,Li, Zhipeng,Xu, Xuemei,Hu, Liming,Huang, Nianyu,He, Hongqiu
, p. 206 - 213 (2015)
In this publication, we design and report the synthesis of calix[4]arene-based β-diketo derivatives as novel HIV-1 integrase (IN) inhibitors. The target compounds were obtained using Claisen condensation, and their structures were characterized by NMR and
Synthesis, electrochemical and intramolecular charge-transfer properties of 'calix[4]arene-acceptor' diad and triad derivatives
Zeng, Cheng-Chu,Becker, James Y.
, p. 1643 - 1650 (2004)
Calix[4]arenes substituted with various acceptor moieties (naphthoquinone (NQ), tetracyanoanthraquinodimethane (TCNAQ)) have been synthesized. In these derivatives the three-dimensional structure of calix[4]arene acts as a weak electron donor (D), connected via a linear sigma spacer to one or two electroactive acceptor (A) units. The electrochemical behavior of these derivatives has been studied by cyclic voltammetry. The UV-Vis spectrum of the TCNAQ triad (A-D-A, 13) reveals the presence of a weak intramolecular charge transfer absorption band.
Synthesis and characterisation of asymmetrically bridged calix[4]arene and tetrathiacalix[4]arene mono amido crown derivatives
Chawla, Harmohinder,Pant, Nalin,Kumar, Satish,Singh, Suneel Pratap
, p. 375 - 378 (2010)
The synthesis of asymmetrically bridged calix[4]arene and tetrathiacalix[4]arene amido crown derivatives has been achieved by the aminolysis of distal diester derivatives of calix[4]arene and tetrathiacalix[4]arene with 1,2-diaminopropane or 1,2-diaminocyclohexane (stereoisomeric mixture, mainly trans). The title compounds have been characterised by detailed analysis of their NMR spectra. The assignment of NMR signals and stereo differentiation in the amido crown ring formation has been studied using a chiral shift reagent.
Synthesis of calix[4]arene-Cryptand hybrid systems: A new generation of hosts for metal ions and molecules
Bandyopadhyay, Prasun,Bharadwaj, Parimal K.
, p. 1331 - 1332 (1998)
A Cryptand with derivatizable secondary amino nitrogens has been successfully coupled to the lower rim of a calix[4]arene through different spacer units.
Novel bis-calix[4]arene based molecular probe for ferric iron through colorimetric, ratiometric, and fluorescence enhancement response
Chawla, Har Mohindra,Gupta, Tanu
, p. 793 - 796 (2015)
A new bis-calix[4]arene platform (4) formed by upper rim-upper rim linking of two calixarene units has been obtained by 1:1 condensation of diformyl calixarene with carbohydrazide. The synthesized bis-calixarene has been found to selectively sense Fe
Metal complexation of calix[4]azacrown derivatives - Evidence for communication between upper and lower functionalised rims
Bond, Andrew D.,Creaven, Bernadette S.,Donlon, Denis F.,Gernon, Tammy L.,McGinley, John,Toftlund, Hans
, p. 749 - 756 (2007)
The coordination chemistry of calix[4]azacrowns obtained from the reaction of a diester calix[4]arene with diethylenetriamine provided unusual copper(II) and manganese(II) complexes in which calix[4]azacrown acts as a bidentate N,O-donor ligand, in some cases, but as a unidentate N-donor ligand, in other cases. The first example of a binuclear ruthenium(II)/manganese(II) complex, involving the calix[4]arene framework as the bridging ligand, is also reported. The calix[4]arene framework consists of a bipyridyl unit connected at the upper rim of the calix[4]arene, through an amide linkage, and an azacrown unit at the lower rim, also connected through amide groups. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Molecular design of calix[4]arene-based extractants which show high Ca2+ selectivity
Ogata, Michiko,Fujimoto, Kiyoshi,Shinkai, Seiji
, p. 4505 - 4506 (1994)
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Fabrication of calixarene based protein scaffold by electrospin coating for tissue engineering
Cagil, Esra Maltas,Ozcan, Fatih,Ertul, Seref
, p. 5292 - 5298 (2018/02/28)
In this study, calixarene was synthesized by using different functional groups as p-tert-butyl- Calix[4]arene ester and amides. Calixarene nanofibers were produced by electrospin coating. Protein immobilization onto the calixarene nanofibers was carried out with human serum albumin (HSA). The maximum amount of binding on produced three different calixarene nanofibers (DE, 2-AMP and 3-AMP) was compared by using a fluorescence technique for protein analysis. Result showed that maximum binding amount was found to be as 177.85 mg cm-2 for 3-AMP surface. The protein binding was also characterized by using SEM, TEM, AFM and FT-IR. From obtained results, calixarene-albumin nanofiber was also fabricated by spin coating using 3-AMP which has ability max binding of protein.
