97602-72-7

Basic information

• Product Name: 1H-Imidazole-4-carboxylicacid,2-methyl-,methylester(9CI)
• Synonyms: 1H-Imidazole-4-carboxylicacid,2-methyl-,methylester(9CI)
• CAS NO: 97602-72-7
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.14
• Product Categories: CARBOXYLICESTER
• Mol File: 97602-72-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Imidazole-4-carboxylicacid,2-methyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-4-carboxylicacid,2-methyl-,methylester(9CI)(97602-72-7)
• EPA Substance Registry System: 1H-Imidazole-4-carboxylicacid,2-methyl-,methylester(9CI)(97602-72-7)

Safety Data

• Hazardous Substances Data: 97602-72-7(Hazardous Substances Data)

Usage

Structure

1H-Imidazole-4-carboxylic acid derivative with a methyl ester group and a methyl group attached to the second carbon of the imidazole ring.

Type of compound

A chemical compound and a valuable reagent.

Common uses

Synthesis of pharmaceuticals, organic chemistry reactions, drug discovery and development, and preparation of various bioactive compounds.

Fields of application

Medicine, research, and scientific study.

Upstream product

• 97602-58-9 methyl (E)-3-(5-methyltetrazol-1-yl)propenoate 
• 67-56-1 methanol 
• 1457-58-5 2-methyl-1H-imidazole-4-carboxylic acid 
• 118493-85-9 acetamide oxime 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 131077-90-2 Methyl 1-(2,4-dibromophenyl)-2-methylimidazole-4-carboxylate 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

Two-step Synthesis of Imidazoles from Activated Alkynes

Conjugate addition of 2-(tri-n-butylstannyl)tetrazoles (1) to activated alkynes gives 1-alkenyltetrazoles (4) and (5) predominantly.Use of the N-tributylstannyl derivatives, rather than the parent tetrazole, gives a high ratio of 1- to 2-alkenyl isomers and avoids the complication of further addition of the tetrazole or the alkyne to the initial adduct.Irradiation of the (Z)- and (E)-1-alkenyltetrazoles (4) and (5) at 254 nm then gives the expected imidazoles in moderate yield.However, 5-phenyl-2-(tri-n-butylstannyl)tetrazole (1a) reacted only slowly with ethyl phenylpropiolate to give ethyl 3,5-diphenylpyrazole-4-carboxylate (8), presumably via the 2-alkenyltetrazole (9) formed in preference to the 1-isomer for steric reasons.