97608-11-2Relevant academic research and scientific papers
Newly-generated Al(OH)3-supported Pd nanoparticles-catalyzed Stille and Kumada coupling reactions of diazonium salts, (Het)aryl chlorides
Li, Xing,Zhu, Tingting,Shao, Zhongqi,Li, Yingjun,Chang, Honghong,Gao, Wenchao,Zhang, Yongli,Wei, Wenlong
supporting information, p. 69 - 75 (2015/12/23)
A ligand-free Pd/Al(OH)3 nano-catalyst which is prepared by one-pot three-component method using Pd(PPh3)4, tetra (ethylene glycol), and aluminum tri-sec-butoxide exhibits excellent catalytic activity in Stille cross-couplings of (Het)aryl chlorides, arenediazonium tetrafluoroborate salts with phenyltributylstannane, respectively, and Kumada couplings of (Het)aryl chlorides with various Grignard reagents. More importantly, these two processes show excellent functional group compatibility with moderate to good yields and they are also versatile with respect to not only (Het)aryl chlorides, but also diazonium salts, and heteroaryl Grignard reagents. The nano-catalyst could also be recycled and reused 5 times without loss of activity and decrease of yield.
Carboxyamido/carbene ligated palladium (II) complex: A versatile catalyst for the synthesis of aryl-substituted heteroarenes
Vishnuvardhan Reddy, Police,Parsharamulu, Thupakula,Annapurna, Manne,Likhar, Pravin R.,Kantam, Mannepalli Lakshmi,Bhargava, Suresh
supporting information, p. 150 - 153 (2016/12/06)
Carboxy amido/carbene ligated Pd-complex catalyzed Suzuki-Miyaura cross-coupling of aryl-boronic acids with heteroaryl bromides is described. The protocol has a broad substrate scope that includes electron-rich, electron-deficient and sterically hindered arylboronic acids and heteroaryl bromides. The catalytic activity of the catalyst has been further investigated in the coupling of 2,6-dibromopyridine with arylboronic acids.
Triarylbismuthanes as threefold aryl-transfer reagents in regioselective cross-coupling reactions with bromopyridines and quinolines
Rao, Maddali L.N.,Dhanorkar, Ritesh J.
supporting information, p. 5214 - 5228 (2014/10/15)
Cross-coupling studies using bromopyridines and bromoquinolines with triarylbismuths as threefold coupling reagents in substoichiometric amounts under Pd-catalysed conditions are disclosed. The reactivity was high with both mono- and dibromopyridyl substrates, and mono- and bis-couplings were carried out regioselectively. A library of monoaryl and diaryl pyridines was formed in high yields. A one-pot strategy provided a simple and straightforward synthesis of both symmetrical and unsymmetrical diarylpyridines. Arylations of 2-bromo- and 3-bromoquinolines were achieved with triarylbismuth reagents. This study demonstrates that triarylbismuths may be used as threefold arylating reagents for the synthesis of aryl pyridines and quinolines through couplings with bromopyridines and bromoquinolines under Pd-catalysed conditions. Copyright
Reaction of Organoboron Compounds with Organic Halides in Aqueous Media, Catalyzed by "Ligand-Free" Palladium
Bumagin,Bykov
, p. 1925 - 1938 (2007/10/03)
The results of investigations of the reactions between aryllboric acids or sodium tetraphenylborate and organic halides in water and DMF- and acetone-water mixtures, catalyzed by palladium salts containing no phosphine ligands [Pd(OAc)2, PdCl2], are considered.
PALLADIUM-CATALYZED CROSS-COUPLING OF PHENYLBORONIC ACID WITH HETEROCYCLIC AROMATIC HALIDES
Stavenuiter, Johannes,Hamzink, Martin,Hulst, Rob van der,Zomer, Gijsbert,Westra, Gerard,Kriek, Erik
, p. 2711 - 2716 (2007/10/02)
The coupling reaction of bromo- and iodopyridines 1 with phenylboronic acid (2a) by Pd(Ph3P)4 provides a convenient route to phenylpyridines, even when electrodonating or - withdrawing substituents are present.The method is also successful for the preparation of other phenylated N-containing heterocycles 5 as phenylquinolines and -pyridines.
