97625-48-4

Upstream product

• 31645-22-4 4-benzyloxy-2,2,6,6-tetramethylpiperidin-1-oxyl 
• 45985-24-8 TEMPOL 

Downstream Products

• 99232-63-0 4-(benzyloxy)-2,2,6,6-tetramethylpiperidine-1-oxide tetrabutylammonium salt 
• 799271-43-5 N¹-acetoxy-2,2,6,6-tetramethylpiperidin-4-yl 2,3,4,6-tetra-O-benzyl-α-D-glucopyranoside 
• 799271-44-6 N¹-acetoxy-2,2,6,6-tetramethylpiperidin-4-yl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

THE USE OF STABLE LIPOPHILIC HYDROXYLAMINE COMPOUNDS FOR INHIBITING POLYMERIZATION OF VINYL MONOMERS

The present invention generally relates to compounds and methods for inhibiting the radical polymerization of unsaturated compounds, particularly vinyl monomers. More particularly, it relates to the use of stable hydroxyl amines to inhibit the polymerization of unsaturated compounds (e.g., vinyl monomers) wherein said stable hydroxylamine is soluble in organic solvents, particularly hydrocarbon solvents consisting of unsaturated and, therefore, polymerizable constituents.

Synthesis and enzyme-catalyzed hydrolysis of a radical-masked glycosylated spin-label reagent

N1-Acetoxy-2,2,6,6-tetramethylpiperidin-4-yl 2,3,4,6-tetra-O-benzyl-α- and -β-d-glucopyranosides (3-α, β) and N1-acetoxy-2,2,5,5-tetramethylpyrrolin-3-oyl 2,3,4,6-tetra-O-benzyl-α- and -β-d-glucopyranosylamines (9-α, β) were synthesized in good yield by Schmidt's glycosylation method. Their subsequent O-debenzylation was proceeded successfully to give the desired products 1-α, and 1-β in good yield, and 2-α in a low yield, without 2-β by only short-timed hydrogenolysis in the presence of palladium-on-carbon (Pd-C) in a CHCl3-MeOH solvent system that included concentrated HCl. Upon enzyme-catalyzed hydrolysis, only 2-α was hydrolyzed by the esterase, while both of 1-α and 1-β were not hydrolyzed by any other enzyme such as lipase. These 2-α can likely be used as a new water-soluble radical-masked glycosylated spin-label reagent.