97627-84-4Relevant academic research and scientific papers
Total Synthesis of Symbioramide, a Novel Ca(2+)-ATPase Activator from Symbiodinium sp.
Yoshida, Jun,Nakagawa, Masako,Seki, Hiroko,Hino, Tohru
, p. 343 - 350 (2007/10/02)
The first total synthesis of symbioramide 1 has been accomplished by the coupling of D-erythro-dihydrosphingosine with an unusual, chiral α-hydroxy-β,γ-unsaturated fatty acid prepared from L-ascorbic acid, and simultaneously established the complete stereostructure of 1 to be (2S,2'R,3R,3'E)-N-(2'-hydroxyoctadec-3'-enoyl)dihydrosphingosine.
A New Convenient Method for the Synthesis of Chiral C3-Synthons
Emons, Carry H.H.,Kuster, Ben F.M.,Vekemans, Jozef A.J.M.,Sheldon, Roger A.
, p. 359 - 362 (2007/10/02)
Routes are described for the facile preparation of protected optically pure D- and L-glyceric acid (1a,b; 2a,b) starting from D-mannitol, D-isoascorbic acid and L-ascorbic acid.The key step is a ruthenium catalyzed oxidative cleavage of the vicinal diols 4a,b or the α-hydroxy acids 7a,b; 10a,b.
A Novel Synthesis of (R)- and (S)-4-Hydroxytetrahydrofuran-2-ones
Tanaka, Akira,Yamashita, Kyohei
, p. 570 - 573 (2007/10/02)
A practical synthesis of (R)- and (S)-4-hydroxytetrahydrofuran-2-ones is accomplished starting from L-ascorbic acid and D-isoascorbic acid, respectively.
