97691-22-0

Upstream product

• 1008-88-4 3-phenylpyridine 
• 38442-51-2 tert-butylmercury chloride 
• 156020-80-3 2,2-dichloro-1-phenylcyclopropanecarbaldehyde diethyl acetal 
• 122801-51-8 2,2-dichloro-1-phenylcyclopropane-1-carbaldehyde 
• 80234-04-4 2-phenylacrylaldehyde diethyl acetal 
• 5813-64-9 2.2-dimethylpropylamine 
• 122-78-1 phenylacetaldehyde 
• 156021-03-3 [1-(2,2-Dichloro-1-phenyl-cyclopropyl)-meth-(E)-ylidene]-(2,2-dimethyl-propyl)-amine 

Relevant academic research and scientific papers

Cross Mannich Reaction of Aldehydes; Efficient Synthesis of Substituted Pyridines

Symmetrically and unsymmetrically substituted pyridines were obtained in highly efficient one-pot procedures starting from α-unbranched aldehydes and iminium salts.

Acid- or base-promoted photostimulated homolytic tert-butylation of pyridines and thiophenes

Regioselective photostimulated homolytic tert-butylations for heteroaromatics such as pyridines or thiophenes are investigated with tert-butylmercury(II) chloride in the presence of toluene-p-sulfonic acid (PTSA) or 1,4-diaza-bicyclo[2.2.2]octane (DABCO)

Thermal Rearrangement of N-Arylmethyl- and N-Alkyl-2,2-dihalogenocyclopropyl Imines

An extended study of the thermal isomerization of 1-substituted 2,2-dihalogenocyclopropyl imines is reported.The thermolysis of N-arylmethyl-2,2-dichlorocyclopropanecarbaldimines 15a-h produces 2-aryl- 16a-h and 2-aryl-4-chloro-pyridine derivatives 17a-h, while N-cyclopropyl imines 15i, j yielded N-alyklchloropyrroles.The 2,2-dibromocyclopropane analogue undergoes thermolysis at lower temperatures.An ionic mechanism triggered by the halide ion dissociation is proposed for the thermal rearrangement on the basis of a study using deuterated imine 15m, and the effects of additives and solvents.On the other hand, difluorocyclopropyl imine undergoes a homolytic cleavage of cyclopropane 1,3-bond with lower activation energy than the dichlorocyclopropyl imine, and afforded the N-alykl-3-fluoropyrrole derivative preferentially.

Alkylation of Pyridine in Free Radical Chain Reactions Utilizing Alkylmercurials

Pyridines or N,N,N',N'-tetramethyl-p-phenylenediamine will undergo a photostimulated free radical chain reaction with alkylmercury halides or carboxylates, yielding ring alkylated substitution products.Alkene mercuration products (R1CH(Y)CH(R2)HgX with Y=HO, RO, CH3CONH; X=Cl, CH3CO2, CF3CO2) can be used without isolation for the alkylation reaction