97704-19-3Relevant academic research and scientific papers
Application of the reetz reagent, dichlorodimethyltitanium, to develop sterically congested quaternary centers. The synthesis of herbertene
Poon, Thomas,Mundy, Bradford P.,Favaloro, Frank G.,Goudreau, Christina A.,Greenberg, Andrew,Sullivan, Ryan
, p. 832 - 834 (1998)
A general protocol for conversion of a tetrasubstituted alkene to a highly methylated hydrocarbon is tested with a concise synthesis of the natural product, herbertene. The conversion: alkene → 1,2-diol → 1,2- dimethylated hydrocarbon should find application in a number of synthesis designs.
