97729-12-9

Upstream product

• 4206-67-1 iodo(trimethylsilyl)methane 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 97729-19-6 2-(3-Oxo-cyclohexylmethyl)-benzoic acid methyl ester 
• 97729-14-1 2,3,3a,9a-Tetrahydro-4H-cyclopenta[b]naphthalene-1,9-dione 
• 97729-18-5 2-[2-(2-Methoxycarbonyl-phenyl)-1-phenyl-ethyl]-malonic acid dimethyl ester 
• 91416-33-0 2,3-dicarbomethoxytetral-1-one 
• 97729-15-2 2-(2-Methoxycarbonyl-benzyl)-succinic acid dimethyl ester 
• 114474-05-4 methyl 2-benzoate 
• 162404-50-4 2-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxycarbonyl-phenyl)-ethyl]-malonic acid benzyl ester methyl ester 
• 60040-81-5 trans-dimethyl 2,2'-(ethene-1,2-diyl)dibenzoate 

Relevant academic research and scientific papers

Synthesis of functionalized benzylsilanes from arylzinc compounds and (iodomethyl)trimethylsilane by means of a novel Rh catalysis

The catalytic activity of a Rh complex in cross-coupling between ArZnI and TMSCH2l was examined in which the Rh complex, generated in situ from [RhCl(1,5-cyclooctadiene)]2 and 1,1′-bis(diphenylphosphino)- ferrocene, exhibited excellent catalytic activity for the production of various functionalized benzylsilanes in good yields. From 31P NMR studies of various solutions containing several of the reaction components, confirmation of the rapid and quantitative transfer of aryl groups from ArZnI to the Rh complex to form arylrhodium species was ascertained. A catalytic cycle, commencing with the transmetalation, was thus proposed for the reaction.

A NEW FLUORIDE ANION-PROMOTED 1,4-CYCLOADDITION LEADING TO SYNTHESIS OF α-TETRALONES

Fluoride anion-promoted 1,4-cycloaddition of methyl o-trimethylsilylmethylbenzoate to conjugated olefins was found to give α-tetralones and uncyclized Michael adducts in moderate yields.