97744-44-0 Usage
Uses
Used in Pharmaceutical Industry:
O-Benzylfluorescein benzyl ester is used as a diagnostic tool for detecting changes in catalytic activity caused by medication, drugs, or the onset of disease. Its fluorescence property allows for the monitoring of enzyme activity and the assessment of drug metabolism, which is crucial for understanding drug interactions and potential side effects.
Used in Research and Development:
In the field of research and development, O-Benzylfluorescein benzyl ester is employed as a substrate to study the function and regulation of cytochrome P450 enzymes. This helps scientists gain insights into the mechanisms of drug metabolism and the development of new pharmaceutical compounds.
Used in Environmental Monitoring:
O-Benzylfluorescein benzyl ester can also be utilized in environmental monitoring to detect the presence of pollutants or contaminants that may affect the activity of cytochrome P450 enzymes. This can provide valuable information on the impact of environmental factors on human health and the ecosystem.
Check Digit Verification of cas no
The CAS Registry Mumber 97744-44-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,7,4 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 97744-44:
(7*9)+(6*7)+(5*7)+(4*4)+(3*4)+(2*4)+(1*4)=180
180 % 10 = 0
So 97744-44-0 is a valid CAS Registry Number.
97744-44-0Relevant academic research and scientific papers
CHIRAL PRODYES. ETHERS AND ESTERS OF DIHYDROFLUORESCEIN, PART 1: DIBENZYLDIHYDROFLUORESCEIN (DBDF) A NEW REAGENT
Tadic, Dragana,Brossi, Arnold
, p. 1975 - 1982 (2007/10/02)
Ethers and esters of dihydrofluorescein (4) were prepared by chemical modification of the benzyl ester (6), obtained by benzylation of fluorescein (1), and reduction of benzyl ester (3) with sodium borohydride.
Photon harvesting polymers: intracoil energy transfer in anthryl- and fluorescein-tagged polystyrene
Hargreaves, J. S.,Webber, S. E.
, p. 1320 - 1327 (2007/10/02)
Polystyrene containing small mole fractions of pendent 9,10-diphenylanthracene (DPA) and fluorescein (F) was prepared.Absorption of light by DPA results in very efficient intracoil sensitization of the 1F* state.The quantum efficiency (χ) of this process has been estimated as 0.75 in dimethylformamide (DMF) and 0.95 in 5:1 DMF/H2O.The increase in χ in this latter solvent mixture is ascribed to the diminished polymer coil size in this poorer sovent.Analysis of the time dependence of fuorescence suggests a combined static and dynamic quenching of 1(DPA)* by energy transfer.Studies of 1(DPA)* and 1(F)* fluorescence quenching by DABCO corroborate this model.