97776-79-9

Upstream product

• 40733-11-7 L-arabinose dibenzyl dithioacetal 
• 77-76-9 2,2-dimethoxy-propane 
• 5328-37-0 L-arabinose 
• 100-53-8 phenylmethanethiol 
• 67-64-1 acetone 

Downstream Products

• 106757-55-5 (E)-3-((R)-2,2-dimethyl[1,3]-dioxolan-4-yl)acrylic acid methyl ester 
• 106757-57-7 (R,E)-3-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)prop-2-en-1-ol 
• 119814-58-3 (R)-4-((E)-3-Benzenesulfonylmethoxy-propenyl)-2,2-dimethyl-[1,3]dioxolane 
• 122410-16-6 (R)-2,2-Dimethyl-4-((E)-3-phenylsulfanylmethoxy-propenyl)-[1,3]dioxolane 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 

Relevant academic research and scientific papers

STEREOCONTROLLED SYNTHESIS OF A C14-C20 BUILDING BLOCK FOR AMPHOTERICIN B USING A NOVEL WITTIG REARRANGEMENT

The C14-C20 unit 11 of the polyene macrolide antibiotic amphotericin B (1) was synthesized from L-arabinose in 13 steps.The key step 7 -> 10 features diastereocontrol through asymmetric induction in a novel Wittig rearrangement.

A Convenient Synthesis of Four Stereoisomers of 6-Acetoxy-5-hexadecanolide, the Major Component of the Mosquito Oviposition Attractant Pheromone

The major component of the mosquito oviposition attractant pheromone (5S,6R)-(+)- and (5R,6S)-(-)-erythro-6-acetoxy-5-hexadecanolide and their threo-isomers, (5R,6R)-(+)- and (5S,6S)-(-)-6-acetoxy-5-hexadecanolide were synthesized from isopropylidene-D-glyceraldehyde and isopropylidene-L-glyceraldehyde, respectively, in which the nucleophilic addition of Grignard reagent involved the diastereoface-differentiating process as the key step.The bioassay of four erythro- and threo-isomers against mosquito (Culex pipiens molestus) was conducted. (5R,6S)-(-)-erythro-6-acetoxy-5-hexadecanolide proved to be the most effective as an attractant.