97840-40-9

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(3-chlorophenoxy)piperidine is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structure and reactivity, contributing to the development of new drugs with potential therapeutic applications.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 4-(3-chlorophenoxy)piperidine serves as a building block for the synthesis of a range of organic compounds, leveraging its distinct chemical properties to create novel molecules with specific functions.
Used in Research and Development:
4-(3-chlorophenoxy)piperidine is utilized as a research compound in the exploration of its potential pharmacological activities, particularly its effects on the central nervous system and as a potential drug target for the treatment of certain neurological disorders.
Used in Material Science:
4-(3-chlorophenoxy)piperidine may also be employed as a component in the development of new materials and chemical processes, where its chemical properties can be harnessed to enhance material properties or create innovative chemical pathways.

InChI:InChI=1/C11H14ClNO/c12-9-2-1-3-11(8-9)14-10-4-6-13-7-5-10/h1-3,8,10,13H,4-7H2

Upstream product

• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 108-43-0 3-monochlorophenol 
• 552868-09-4 tert-butyl 4-(3-chlorophenoxy)piperidine-1-carboxylate 
• 97840-41-0 N-(2-bromoacetyl)-4-(m-chlorophenoxy)piperidine 

Downstream Products

• 97840-41-0 N-(2-bromoacetyl)-4-(m-chlorophenoxy)piperidine 
• 330669-71-1 (R)-1-[4-(3-chloro-phenoxy)-piperidin-1-yl]-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol 
• 330669-84-6 (R)-1-[4-(3-chloro-phenoxy)-piperidin-1-yl]-3-(3-isoxazolo[5,4-b]pyridin-3-yl-phenoxy)-propan-2-ol 

Relevant academic research and scientific papers

PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS

The present invention relates to novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as prostaglandin E2 (PGE2) EP4 receptor antagonists, which renders them highly advantageous for use in therapy, particularly in the treatment or prevention of cancer, a neovascular eye disease, inflammatory pain, or an inflammatory disease, such as, e.g., multiple sclerosis, rheumatoid arthritis or endometriosis.

DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS

Compounds of formula I: I are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF

Disclosed herein are compounds of Formula I as defined herein, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, that modulates the activity of a ghrelin receptor. Disclosed herein are also methods of treating diseases or conditions that comprise administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I.

Analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines

There are described analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines of the formula STR1 where X is hydrogen, loweralkyl, CF3, acetyl or halogen; n is 1 or 2; R1 is H2 or oxygen; R2 is H, loweralkyl

Piperidylalkylindoles. 1. Hypotensive activity of 3-[2-(phenoxypiperidyl)ethyl]indoles

A series of 3-[2-(phenoxypiperidyl)ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.