97840-40-9

Basic information

• Product Name: 4-(3-CHLOROPHENOXY)PIPERIDINE
• Synonyms: Piperidine, 4-(3-chlorophenoxy)-;4-(3-Chlorophenoxy)
• CAS NO: 97840-40-9
• Molecular Formula: C₁₁H₁₄ClNO
• Molecular Weight: 211.69
• Mol File: 97840-40-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 312.8°C at 760 mmHg
• Flash Point: 143°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 0.000518mmHg at 25°C
• Refractive Index: 1.538
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-(3-CHLOROPHENOXY)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-CHLOROPHENOXY)PIPERIDINE(97840-40-9)
• EPA Substance Registry System: 4-(3-CHLOROPHENOXY)PIPERIDINE(97840-40-9)

Safety Data

• Hazardous Substances Data: 97840-40-9(Hazardous Substances Data)

Usage

General Description

4-(3-chlorophenoxy)piperidine is a chemical compound that consists of a piperidine ring with a 3-chlorophenoxy group attached to the fourth carbon atom. It is used in the synthesis of various pharmaceuticals and organic compounds due to its unique structure and reactivity. 4-(3-chlorophenoxy)piperidine has been studied for its potential pharmacological activities, including its effects on the central nervous system and as a potential drug target for the treatment of certain neurological disorders. Additionally, 4-(3-chlorophenoxy)piperidine may also be used as a building block in the development of new materials and chemical processes. Its chemical properties and potential applications make it a valuable compound for research and development in the fields of chemistry and pharmaceutical science.

InChI:InChI=1/C11H14ClNO/c12-9-2-1-3-11(8-9)14-10-4-6-13-7-5-10/h1-3,8,10,13H,4-7H2

Upstream product

• 552868-09-4 tert-butyl 4-(3-chlorophenoxy)piperidine-1-carboxylate 
• 108-43-0 3-monochlorophenol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 97840-41-0 N-(2-bromoacetyl)-4-(m-chlorophenoxy)piperidine 

Downstream Products

• 97840-41-0 N-(2-bromoacetyl)-4-(m-chlorophenoxy)piperidine 
• 330669-84-6 (R)-1-[4-(3-chloro-phenoxy)-piperidin-1-yl]-3-(3-isoxazolo[5,4-b]pyridin-3-yl-phenoxy)-propan-2-ol 
• 330669-71-1 (R)-1-[4-(3-chloro-phenoxy)-piperidin-1-yl]-3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-propan-2-ol 

Relevant articles and documents

PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS

The present invention relates to novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as prostaglandin E2 (PGE2) EP4 receptor antagonists, which renders them highly advantageous for use in therapy, particularly in the treatment or prevention of cancer, a neovascular eye disease, inflammatory pain, or an inflammatory disease, such as, e.g., multiple sclerosis, rheumatoid arthritis or endometriosis.

BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF

Disclosed herein are compounds of Formula I as defined herein, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, that modulates the activity of a ghrelin receptor. Disclosed herein are also methods of treating diseases or conditions that comprise administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I.

Piperidylalkylindoles. 1. Hypotensive activity of 3-[2-(phenoxypiperidyl)ethyl]indoles

A series of 3-[2-(phenoxypiperidyl)ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.