97845-33-5Relevant academic research and scientific papers
SELECTIVE ELECTROPHILIC MONOFLUORINATION ON RINGS OF VARIOUS SIZES USING ELEMENTAL FLUORINE
Rozen, Shlomo,Gal, Chava
, p. 143 - 148 (1985)
Elemental fluorine substitutes tertiary unactivated hydrogens in an electrophilic mode.This unorthodox substitution depends on the atomic charge density, on the hydrogen atom and on the p-orbital contribution on the C-H bond.This is demonstrated by reacti
Activating Unreactive Sites of Organic Molecules Using Elemental Fluorine
Rozen, Shlomo,Gal, Chava
, p. 2769 - 2779 (2007/10/02)
Electrophilic substitution reactions on saturated carbons are extremely rare.Elemental fluorine, however, uses this pathway to replace tertiary unactivated hydrogens with great regio- and stereoselectivity, resulting in a full retention of configuration.I
