97881-32-8

Basic information

• Product Name: 2-(di-o-tolyl-boranyloxy)-ethylamine
• Synonyms: 2-(di-o-tolyl-boranyloxy)-ethylamine
• CAS NO: 97881-32-8
• Molecular Weight: 253.152
• Mol File: 97881-32-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(di-o-tolyl-boranyloxy)-ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(di-o-tolyl-boranyloxy)-ethylamine(97881-32-8)
• EPA Substance Registry System: 2-(di-o-tolyl-boranyloxy)-ethylamine(97881-32-8)

Safety Data

• Hazardous Substances Data: 97881-32-8(Hazardous Substances Data)

Upstream product

• 121-43-7 Trimethyl borate 
• 95-46-5 2-methylphenyl bromide 
• 141-43-5 ethanolamine 
• 73774-44-4 bis(2-methylphenyl)borinic acid 
• 932-31-0 ortho-tolylmagnesium bromide 

Downstream Products

• 73774-44-4 bis(2-methylphenyl)borinic acid 
• 56917-39-6 4-acetyl-2'-methylbiphenyl 
• 893738-92-6 4-benzyloxy-2'?-methylbiphenyl 

Relevant articles and documents

Cross-coupling of diarylborinic acids and anhydrides with arylhalides catalyzed by a phosphite/N-heterocyclic carbene co-supported palladium catalyst system

A highly efficient cross-coupling of diarylborinic acids and anhydrides with aryl chlorides and bromides has been effected by using a palladium catalyst system co-supported by a strong σ-donor N-heterocyclic carbene (NHC), N,N′-bis(2,6-diisopropylphenyl) imidazol-2-ylidene, and a strong π-acceptor phosphite, triphenylphosphite, in tert-BuOH in the present of K3PO4·3H2O. Unsymmetrical biaryls with a variety of functional groups could be obtained in good to excellent yields using as low as 0.01, 0.2-0.5, and 1 mol % palladium loadings for aryl bromides and activated and deactivated aryl chlorides, respectively, under mild conditions. A ligand synergy between the σ-donor NHC and the π-acceptor phosphite in the Pd/NHC/P(OPh)3 catalytic system has been proposed to be responsible for the high efficacy to arylchlorides in the cross-coupling. A scalable and economical process has therefore been developed for synthesis of Sartan biphenyl from the Pd/NHC/P(OPh)3 catalyzed cross-coupling of di(4-methylphenyl)borinic acid with 2-chlorobenzonitrile.

Synthesis and anticoccidial activity of some azacyclo organoborinates

A series of azacyclo organoborinates derivatives of piperidinyl and pyridinyl alcohols were prepared and their anticoccidial activity was tested in vitro assay system. Among them, di(4-chlorophenyl)(2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)(2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)(2-pyridinylmethoxy-O,N)boron, and di(3-trifluoromethylphenyl)(2-pyridinylethoxy-O,N)boron, showed moderate anticoccidial activity against Eimeria tenella.