97888-75-0Relevant academic research and scientific papers
Synthesis method of 2-arylformyl-1-arylethanone derivative
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Paragraph 0022, (2017/03/08)
The invention discloses a synthesis method of 2-arylformyl-1-arylethanone derivative shown by the formula (I). The synthesis method comprises the following steps: in a reaction solvent and with an omega-bromoacetophenone compound shown by the formula (II)
PHENYLETHANOLAMINE DERIVATIVES, III. SYNTHESIS OF 1-(HYDROXY- AND METHOXYPHENYL)-2-AMINOETHANOL DERIVATIVES
Hajoos, Andor
, p. 63 - 70 (2007/10/02)
New 1-(methoxyphenyl)- and 1-(hydroxyphenyl)-2-aminoethanol derivatives have been prepared for the purpose of biological testing.The compounds were obtained via aminolysis of the corresponding phenacyl halides and subsequent reduction of the resulting phenacylamines with sodium tetrahydridoborate.In the aminolysis of phenacyl halides O-benzoyl-ω-hydroxyaminoacetophenones and 1,2-dibenzoylethanes were formed as by-products.In some cases the 4-methoxy-ω-aminoacetophenones were hydrolyzed by aqueous hydrogen bromide into the corresponding glycine and phenol.
