97914-59-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(Difluoromethoxy)benzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved therapeutic properties. Its incorporation into drug molecules can enhance their efficacy, selectivity, and pharmacokinetic profiles.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(difluoromethoxy)benzoic acid serves as a crucial building block for the creation of novel agrochemicals, including pesticides and herbicides. Its unique chemical structure can potentially lead to the development of more effective and environmentally friendly agricultural products.
Used in Materials Science:
2-(Difluoromethoxy)benzoic acid is utilized as a component in the synthesis of advanced materials with specific properties, such as high thermal stability, chemical resistance, or unique optical characteristics. Its presence in these materials can enhance their performance and applicability in various industries.
Used as a Reagent in Organic Chemistry:
2-(Difluoromethoxy)benzoic acid is employed as a reagent in chemical reactions for the synthesis of complex organic molecules. Its reactive functional groups facilitate various synthetic transformations, enabling the preparation of a wide range of organic compounds for research and industrial applications.
Used in Research for Anti-Inflammatory and Antioxidant Properties:
2-(Difluoromethoxy)benzoic acid is studied for its potential anti-inflammatory and antioxidant properties, which could lead to the development of new therapeutic agents for the treatment of inflammation-related diseases and oxidative stress conditions. Its unique structure may contribute to modulating inflammatory pathways and scavenging reactive oxygen species, offering new avenues for medical intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 97914-59-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,9,1 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 97914-59:
(7*9)+(6*7)+(5*9)+(4*1)+(3*4)+(2*5)+(1*9)=185
185 % 10 = 5
So 97914-59-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F2O3/c9-8(10)13-6-4-2-1-3-5(6)7(11)12/h1-4,8H,(H,11,12)
97914-59-5Relevant academic research and scientific papers
Catalytic radical difluoromethoxylation of arenes and heteroarenes
Lee, Johnny W.,Zheng, Weijia,Morales-Rivera, Cristian A.,Liu, Peng,Ngai, Ming-Yu
, p. 3217 - 3222 (2019/03/21)
Intermolecular C-H difluoromethoxylation of (hetero)arenes remains a long-standing and unsolved problem in organic synthesis. Herein, we report the first catalytic protocol employing a redox-active difluoromethoxylating reagent 1a and photoredox catalysts for the direct C-H difluoromethoxylation of (hetero)arenes. Our approach is operationally simple, proceeds at room temperature, and uses bench-stable reagents. Its synthetic utility is highlighted by mild reaction conditions that tolerate a wide variety of functional groups and biorelevant molecules. Experimental and computational studies suggest single electron transfer (SET) from excited photoredox catalysts to 1a forming a neutral radical intermediate that liberates the OCF2H radical exclusively. Addition of this radical to (hetero)arenes gives difluoromethoxylated cyclohexadienyl radicals that are oxidized and deprotonated to afford the products of difluoromethoxylation.
DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME
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Page/Page column 75; 79; 89; 102-103, (2019/09/18)
The present invention provides a compound having the structure (I), a processing of making the compound; and a process of using the compound as a reagent for the difluoromethoxylation and trifluoromethoxylation of arenes or heteroarenes.
