97971-44-3

Upstream product

• 93367-08-9 Kalium-<4S-(R*,S*)>-α-hydroxy-2,2-dimethyl-1,3-dioxolan-4-acetat 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 92973-40-5 methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate 
• 97971-42-1 (R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propane-1,2-diol 
• 97971-43-2 Benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-2-methyl-propyl ester 

Downstream Products

• 97971-47-6 2-(tert-Butyldiphenylsiloxy)-3-methyl-but-3-enal 
• 97971-46-5 3-(tert-Butyldiphenylsiloxy)-4-methyl-but-4-ene-1,2-diol 
• 97971-48-7 Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate 
• 130258-75-2 Ethyl 4(R)-(tert-Butyldiphenylsiloxy)-5,6-epoxy-5(S)-methyl-but-2(E)-enoate 
• 97973-48-3 Ethyl 4(R)-(tert-Butyldiphenylsiloxy)-5,6-epoxy-5(R)-methyl-but-2(E)-enoate 
• 158018-97-4 Benzoic acid (E)-(S)-3-methoxycarbonyl-1-((R)-2-methyl-oxiranyl)-allyl ester 
• 158018-98-5 Benzoic acid (E)-(S)-3-methoxycarbonyl-1-((S)-2-methyl-oxiranyl)-allyl ester 
• 158189-03-8 Benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester 
• 158018-96-3 methyl 4(S)-benzoyloxy-5-methyl-2,5-hexadienoate 
• 158018-95-2 Benzoic acid (R)-1-((S)-1,2-dihydroxy-ethyl)-2-methyl-allyl ester 
• 97971-45-4 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene 

Relevant academic research and scientific papers

Studies on the structure-toxicity relationship of AK-toxin, a host- specific toxin to Japanese white pear, produced by Alternaria kikuchiana: Synthesis of methyl (4S,5R)-4-(N-acetylphenylalanyl)oxy-5,6-epoxy-5- methylhex-2(E)-enoate and its stereoisomers

Methyl (4S,5R)-4-(N-acetylphenylalanyl)oxy-5,6-epoxy-5-methylhex-2(E)- enoate, the enantiomeric analogue of AK-toxin, the host-specific toxin, and its stereoisomers have been synthesized and tested for host-specific toxin activity.

An approach to a synthesis of the host-specific toxins AK-toxin I and II, starting from vitamin C as a chiral material

An approach to the synthesis of AK-toxin I and II starting from Vitamin C was investigated. During the course of the approach, the stereostructure of the trienoic acid part of the toxins were revealed to be 8(R),9(S)- or 8(S),9(R)-9,10-epoxy-9-methyl-8-hy