Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester

Base Information

• Chemical Name: Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester
• CAS No.: 97971-44-3
• Molecular Formula: C₁₆H₂₀O₄
• Molecular Weight: 276.332
• Mol file: 97971-44-3.mol

Synonyms:Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester

Chemical Property of Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester

There total 5 articles about Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

Benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-2-methyl-propyl ester (97971-43-2) → Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester (97971-44-3)

Guidance literature:

With thionyl chloride; In pyridine; for 1h; Ambient temperature;

DOI:10.1248/cpb.42.1328

Reference yield:

(R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propane-1,2-diol (97971-42-1) → Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester (97971-44-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / pyridine / 0.5 h / Ambient temperature

2: 82 percent / thionyl chloride / pyridine / 1 h / Ambient temperature

With pyridine; thionyl chloride; In pyridine;

DOI:10.1248/cpb.42.1328

Reference yield:

methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate (92973-40-5) → Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester (97971-44-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / diethyl ether / 0.5 h / Heating

2: 97 percent / pyridine / 0.5 h / Ambient temperature

3: 82 percent / thionyl chloride / pyridine / 1 h / Ambient temperature

With pyridine; thionyl chloride; In pyridine; diethyl ether;

DOI:10.1248/cpb.42.1328

upstream raw materials:

Benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-2-methyl-propyl ester

(R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propane-1,2-diol

methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate

Kalium-<4S-(R*,S*)>-α-hydroxy-2,2-dimethyl-1,3-dioxolan-4-acetat

Downstream raw materials:

4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

Benzoic acid (R)-1-((S)-1,2-dihydroxy-ethyl)-2-methyl-allyl ester

methyl 4(S)-benzoyloxy-5-methyl-2,5-hexadienoate

Benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester