97985-67-6Relevant academic research and scientific papers
Asymmetric epoxidation of α,β-unsaturated aldehydes catalyzed by a spiro-pyrrolidine-derived organocatalyst
Xu, Ming-Hui,Tu, Yong-Qiang,Tian, Jin-Miao,Zhang, Fu-Min,Wang, Shao-Hua,Zhang, Shi-Heng,Zhang, Xiao-Ming
supporting information, p. 294 - 300 (2017/03/01)
The asymmetric epoxidation of α,β-unsaturated aldehydes, catalyzed by a spiro-pyrrolidine (SPD)-derived organocatalyst, has been accomplished with good diastereoselectivities (up to dr >20:1) and with high to excellent enantioselectivities (up to 99% ee).
Highly diastereoselective formation of 1,2,3-trisubstituted cyclopropane derivatives
Xie, Xingang,Yue, Guoren,Tang, Shouchu,Huo, Xing,Liang, Qiren,She, Xuegong,Pan, Xinfu
, p. 4057 - 4059 (2007/10/03)
(Chemical Equation Presented) A highly diastereoselective formation of cyclopropane derivatives was reported. When the chiral phenylvinyl epoxide reacted with lithiated 2-alkyl-1,3-dithiane or lithiated alkyl carbonanion in the presence of HMPA, cyclopropanes bearing stereochemistry at all three positions on the ring were readily obtained in high yields of 80-97% and high dr values of 68:32-99:1. This reaction was supposed to be a tandem conjugation addition-epoxide opening sequence.
EPOXIDATION OF trans-3-ARYLPROPENALS BY tert-BUTYL HYDROPEROXIDE
Revinskii, I. F.,Tishchenko, I. G.,Burd', V. N.,Bubel', O. N.
, p. 637 - 641 (2007/10/02)
The products and the kinetics of the epoxidation of trans-3-arylpropenals with tert-butyl hydrogen peroxide in an alkaline medium were studied.The epoxidation rate increases with increase in the electron-withdrawing characteristics of the substituents in the aryl fragment of cinnamaldehydes.
