98017-34-6Relevant academic research and scientific papers
Bronsted Acid Mediated Direct α-Hydroxylation of Cyclic α-Branched Ketones
Shevchenko, Grigory A.,Dehn, Stefanie,List, Benjamin
supporting information, p. 2298 - 2300 (2018/10/20)
We report a Bronsted acid mediated direct α-hydroxylation of cyclic α-branched ketones via a tandem aminoxylation/N-O bond-cleavage process. Nitrosobenzene is used as the oxidant and subsequently promotes the liberation of the free alcohol. The desired pr
Iron(iii) chloride hexahydrate-promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of hetero-quaternary scaffolds
Chen, Tao,Peng, Rui,Hu, Wenxin,Zhang, Fu-Min
supporting information, p. 9859 - 9867 (2016/10/31)
A novel and tunable α-hydroxylation/α-chlorination of benzyl ketone derivatives has been developed for the construction of hetero-quaternary carbon centers by iron(iii) chloride hexahydrate mediated selective transformations through the application of dif
Electroreductive acylation of aromatic ketones with acylimidazoles
Kise, Naoki,Agui, Syun,Morimoto, Shinji,Ueda, Nasuo
, p. 9407 - 9410 (2007/10/03)
The intermolecular reductive coupling of aromatic ketones with acylimidazoles was effected by electroreduction in the presence of chlorotrimethylsilane and gave α-trimethylsiloxy ketones and esters. The best result was obtained using Bu4NPF6 as a supporting electrolyte and a Pb cathode in THF. The α-trimethylsiloxy-containing products were transformed to the corresponding α-hydroxy ketones and esters by treatment with TBAF in THF. This method was also effective for the intramolecular reductive coupling of δ- and ε-keto acylimidazoles.
