98061-63-3Relevant academic research and scientific papers
Studies on Heterocyclic Enaminonitriles. VI. Synthesis of 2-Amino-3-cyano-4,5-dihydrofurans
Matsuda, Takumi,Yamagata, Kenji,Tomioka, Yukihiko,Yamazaki, Motoyoshi
, p. 937 - 943 (2007/10/02)
Malononitrile reacts with 2-chloroethanol and 1-chloro-2-propanol (or 2-methyloxirane) in the presence of sodium ethoxide to give 2-amino-3-cyano-4,5-dihydrofuran (Ia) and 2-amino-3-cyano-5-methyl-4,5-dihydrofuran (Ib), respectively.The reaction of malono
