98192-30-4

Upstream product

• 143885-61-4 7-hydroxy-6-(4'-methoxy)cinnamoyl-3,4-dihydro-2,2-dimethyl-2H-benzo(1,2b)pyran 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 97185-30-3 3(4'-hydroxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo(1,2-b:5,4-b')dipyran-4-one 
• 63762-53-8 erythrinin A methyl ether 
• 63807-86-3 alpinumisoflavone 
• 97185-29-0 3-(4'-Methoxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2-b; 5,4.b'>dipyran-4-one 

Relevant academic research and scientific papers

SYNTHESIS OF ERYTHRININ A, A NATURALLY OCCURING PYRANOISOFLAVONE

Erythrinin A (10) has been synthesised by the oxidative rearrangement of dihydropyranochalcone 1 with thallium(III)nitrate (TTN) in trimethyl orthoformate (TMOF) to the dimethyl acetal 2, followed by cyclisation to 3, demethylation to 6 and dehydrogenation.Compound 10 could also be obtained from chalcone 4 on similar rearrangement followed by cyclisation, demethoxymethylation and dehydrogenation.In another route, chalcone 7 was oxidatively rearranged with TTN in TMOF, to 8 which on treatment with HCl yielded 10.