143885-61-4

Basic information

• Product Name: 2-Propen-1-one, 1-(3,4-dihydro-7-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-meth oxyphenyl)-, (2E)-
• CAS NO: 143885-61-4
• Molecular Formula: C21H22O4
• Molecular Weight: 338.403
• Mol File: 143885-61-4.mol

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(3,4-dihydro-7-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-meth oxyphenyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(3,4-dihydro-7-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-meth oxyphenyl)-, (2E)-(143885-61-4)
• EPA Substance Registry System: 2-Propen-1-one, 1-(3,4-dihydro-7-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-meth oxyphenyl)-, (2E)-(143885-61-4)

Safety Data

• Hazardous Substances Data: 143885-61-4(Hazardous Substances Data)

Upstream product

• 78-79-5 isoprene 
• 125116-27-0 7-acetoxy-2,2-dimethyl chroman 
• 108-46-3 recorcinol 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 31273-58-2 1-(7-hydroxy-2,2-dimethylchroman-6-yl)ethanone 
• 104-87-0 4-methyl-benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 31005-72-8 2,2-dimethylchroman-7-ol 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 

Downstream Products

• 97185-29-0 3-(4'-Methoxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo<1,2-b; 5,4.b'>dipyran-4-one 
• 63807-86-3 alpinumisoflavone 
• 97911-95-0 (7-Benzyloxy-2,2-dimethyl-chroman-6-yl)-[3-(4-methoxy-phenyl)-oxiranyl]-methanone 
• 97185-30-3 3(4'-hydroxy)phenyl-8,8-dimethyl-6,7-dihydro-4H,8H-benzo(1,2-b:5,4-b')dipyran-4-one 
• 63762-53-8 erythrinin A methyl ether 
• 98192-30-4 1-(7-Hydroxy-2,2-dimethyl-chroman-6-yl)-3,3-dimethoxy-2-(4-methoxy-phenyl)-propan-1-one 
• 97911-89-2 (E)-1-(7-Benzyloxy-2,2-dimethyl-chroman-6-yl)-3-(4-methoxy-phenyl)-propenone 

Relevant articles and documents

BF3-Et2O mediated biogenetic type synthesis of chromanochalcones from prenylated chalcones via a regioselective cyclization reaction

In continuation of our program on synthetic chalcones, we have developed a simple and convenient method for the synthesis of chromanochalcones from prenylated chalcones in high yields by regioselective cyclization using BF3-Et2O.

Microwave-assisted synthesis and antimicrobial evaluation of novel pyrazolines

A series of 6-(5-aryl-4,5-dihydro-1 H-pyrazol-3-yl)-2,2-dimethylchroman-7-ol and 6-(5-aryl-4,5-dihydro-1 H-pyrazol-3-yl)-2,2-dimethyl-chroman-5-ol derivatives have been synthesized from the corresponding chalcones and hydrazine hydrate in the presence of

Synthesis and characterisation of new chromano pyrimidines and study of antimicrobial activity

The title compounds, (five new chromano pyrimidines) were synthesized by condensation of chalcones with guanidine hydrochloride in the presence of potassium t- butoxide and t-butanol. The synthesis involves following steps- Starting with the acylation of Resorcinol using anhydrous ZnCl2 and glacial acetic acid, which afforded Resacetophenone 1. Resacetophenone was then subjected to nuclear prenylation using isoprene in the presence of polyphosphoric acid and xylene, to form 7-hydroxy-6-acetyl 2,2′-dimethyl Chroman 2. Condensation of Chroman with various substituted benzaldehydes in the presence of alcoholic KOH furnished different chalcones 3-7. Finally, Chalcones were condensed with guanidine hydrochloride in the presence of potassium t- butoxide and t-butanol and the title compounds 8-12 were obtained. Compounds thus obtained were characterized by various spectroscopic techniques to confirm their structures. The title compounds were tested at different concentrations for their antibacterial activity against Gram-positive bacteria Bacillus subtillis and Bacillus pumilus and Gram-negative bacteria Escherichia coli and Proteus vulgaris. Antifungal activity of the title compounds was tested against Rhizopus oryzae and Aspergillus niger at different concentrations. Minimum inhibitory concentration was also determined.

A facile synthesis of acetyl-hydroxy-2, 2-dimethylchromans and 2,2- dimethyl-2H-3,4-dihydropyranoflavanones - Dihydro mixtecacin, atalantoflavone dimethyl ether and racemoflavone dimethyl ether

Synthesis of acetyl-hydroxy-2, 2-dimethyl chromans by thermal-Fries rearrangement of acetoxy-2, 2-dimethylchromans has been described. The reaction of acetyl-hydroxy chromans (2, 4 and 6) with aryl aldehyde in the presence of aqueous ethanolic potassium h

13C Nuclear Magnetic Resonance Studies on Pyrano- and Dihydropyrano-1,3-diphenylprop-2-enones

The 13C NMR spectra of 19 differently substituted pyrano- and dihydropyrano-1,3-diphenylprop-2-enones were recorded and the results are discussed.The data will be useful in the identification of new and natural chalcones. Key Words: Chalcones - 1,3-Diphen

CINNAMOYLATION OF CHROMANS: FORMATION OF FLAVONOIDS AND NEOFLAVONOIDS

Cinnamoylation of chroman 1 with 4 in presence of fused zinc chloride and phosphorus oxychloride gave chalcone 8 and with acids 5-7, the chalcones 9-11 and dihydrocoumarins 15-17 respectively.A similar reaction of chroman 2 with acids 4 and 5 afforded the

Boron Trifluoride Etherate Catalysed Rearrangement of Dihydropyranochalcone Epoxides: Synthesis of Dihydropyranoisoflavones and Their Dehydro-analogs

6-Acetyl-7-hydroxy-2,2-dimethylchroman (I) and 6-acetyl-7-methoxy-2,2-dimethylchroman (II) on condensation with the arylaldehydes (IIIa-d) give the dihydropyranochalcones (IVa-f).The O-benzylated chalcones (Va-f) are oxidised with alkaline hydrogen peroxi