98236-04-5

Upstream product

• 82044-42-6 [4-(2-tert-Butyl-oxaziridin-3-yl)-phenyl]-dimethyl-amine 
• 57497-39-9 N-tertbutylhydroxylamine hydrochloride 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 16649-50-6 N-tert-Butylhydroxylamine 
• 59812-56-5 4-[(E)-(tert-butylimino)methyl]-N,N-dimethylaniline 

Relevant academic research and scientific papers

α-Phenyl-N-tert-butyl nitrone (PBN) derivatives: Synthesis and protective action against microvascular damages induced by ischemia/reperfusion

Nitrones 4-7, structurally related to PBN (1), were prepared by reaction of the corresponding aromatic aldehydes with N-tert-butyl hydroxylamine. The protective effects of these nitrones against microvascular damages in ischemia/reperfusion in the 'hamste

Chromium and Tungsten Pentacarbonyl Groups as Reactivity and Selectivity Auxiliaries in Cycloaddition of Alkynyl Fischer Carbene Complexes with N-Alkyl Nitrones

Alkynyl Fischer carbene complexes were found to undergo chemoselective, regioselective, and rate-enhanced 1,3-dipolar cycloaddition with nitrones to give 2,3-dihydroisoxazole carbene complexes in excellent yields.These alkynyl complexes can serve as synth

1H andd 13C NMR Spectra of (Z)-C-Aryl N-tert-Butyl Nitrones

The 1H an 13C NMR spectra of 12 (Z)-C-aryl N-tert-butyl nitrones were measured and proton and carbon assignments made.The nitrones were synthesized by the dimethyldioxirane method.

Imines and Derivatives. Part 24. Nitrone Synthesis by Imine Oxidation using either a Peroxyacid or Dimethyldioxirane

The oxidation of N-alkyl imines by m-chloroperoxybenzoic acid to yield nitrones was facilitated by (i) the presence of C-aryl substituents, (ii) steric inhibition of attack at the imino C-atom, (iii) electron donating para-substituents on the C-aryl substituent, (iv) non-hydroxylic solvents, (v) optimal conjugation between C-aryl substituents and the imino group, and (vi) less bulky N-alkyl groups. The oxidation of N-alkyl imines by dimethyldioxirane (DMD) in dichloromethane-acetone solution yielded nitrones without evidence of oxaziridine formation.The yields of isolated nitrones were higher for C,C-diaryl imines and for imines bearing less bulky N-alkyl substituents.N-H substituted ketimines were found to yield oximes after reaction with dimethyldioxirane.

NORMAL, ABNORMAL AND PSEUDO-ABNORMAL REACTION PATHWAYS FOR THE IMINE-PEROXYACID REACTION

Steric and mesomeric effects have a marked influence upon the formation of oxaziridine (normal pathway) or nitrone (abnormal pathway) products from the imine-peroxyacid reaction; n.m.r. studies of the thermal isomerization of oxaziridines to nitrones prov

ARYL SUBSTITUENT EFFECTS UPON THE THERMAL ISOMERIZATION OF N-ALKYL OXAZIRIDINES TO NITRONES

The results of a kinetic study of the thermal isomerization of oxaziridines derived from para-substituted C-arylaldimines and C-diarylketimines to the isomeric nitrones is reported.