98262-87-4Relevant academic research and scientific papers
1-Acyldeoxyvasicinone salts as effective intermediate C- and N-acylating agents for alkaloids and amino acids
Shakhidoyatov,Genjemuratova,Oripov
, p. 718 - 723 (2006)
The reaction of deoxyvasicinone with acid chlorides of aliphatic (acetylbromide) and aromatic (benzoyl-, o-, p-methoxy-, p-nitrobenzoylchlorides) acids was studied. It was shown that 1-deoxyvasicinone salts were formed at room temperature; α-aroyloxymethylidenedeoxyvasicinones, in the presence of triethylamine at 80-85°C. It was found that acid chlorides cause 1-acyldeoxyvasicinone salts to transform into α-hydroxy-or α-aroyloxyarylidenedeoxyvasicinones, which indirectly confirmed their acylating properties. It was found that 1-acyldeoxyvasicinone salts were effective acylating agents for alkaloids (cytisine, 1,2-dihydrodeoxyvasicinone) and amino acids (glycine, β-alanine, α-aminobutyric acid) and can be used to acylate primary and secondary aliphatic and heterocyclic amines.
New reactions of Deoxyvasicinone. Part 3.
Dunn, A. D.,Kinnear, K. I.
, p. 311 - 312 (2007/10/02)
The reaction of deoxyvasicinone 1 with benzoic anhydride, bis(dimethylamino)methane and amyl nitrite are reported.Metallation of 1 is also described.
