98288-50-7Relevant academic research and scientific papers
ANTHRANILAMIDE INHIBITORS OF AURORA KINASE
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Page/Page column 39, (2008/12/07)
The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof; where R1, R2, R3, R4, r and s are as previously defined. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
Ar(alk)ylsulfonyl ethyl groups as phosphorus-protecting functions
Claesen, C. A. A.,Segers, R. P. A. M.,Tesser, G. I.
, p. 119 - 122 (2007/10/02)
Various 2-ethanols were prepared and subsequently converted into the corresponding phosphorodichloridites in almost quantitative yield via a convenient synthetic route.The versatility of the method, which obviates the necessity of a distillation step, is demonstrated by the preparation of other (Ar(alk)yl phosphorodichloridites, including the unstable benzyl phosphorodichloridite.
