98387-59-8

Basic information

• Product Name: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester
• Synonyms: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester
• CAS NO: 98387-59-8
• Molecular Weight: 302.368
• Mol File: 98387-59-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester(98387-59-8)
• EPA Substance Registry System: 2-Butyl-3-ethoxycarbonyl-succinic acid diethyl ester(98387-59-8)

Safety Data

• Hazardous Substances Data: 98387-59-8(Hazardous Substances Data)

Upstream product

• 13049-86-0 diethyl 2-(ethoxycarbonylmethylene)malonate 

Relevant articles and documents

Reduction-alkylation with organocopper(I) reagents-alkyl halydes: Highly regioselective α-alkylation of γ-acetoxy-α,β-enoates with lithium dibutylcuprate-alkyl halides and difference in the reactivity of electron-deficient olefins with organocopper(I)-Lewis acid reagents

Reaction of γ-acetoxy-α,β-enoates with lithium dialkylcuprate followed by alkyl halides results in the predominant or exclusive formation of α-alkyl-β,γ-enoates in high yields under mild conditions, and a synthetic application to (+-)-α-vetispirene is presented.Treatment of diethyl fumarate and triethoxycarbonylethylene with Bu2CuLi*AlCl3 led to 1,4-addition to give conjugate adducts in high yields.In sharp contrast, diethyl maleate and tetraethoxycarbonylethylene predominantly gave the respective reduction products.Evidence for a presumed dianionic intermediate, based on trapping with some electrophyles, is also presented.Keywords - γ-oxygenated α,β-enoate; β,γ-enoate; deconjugative reduction; α-vetispirene; lithium dialkylcuprate; organocopper(I)-Lewis acid.