98395-58-5Relevant academic research and scientific papers
Reaction of aldehydes and pyrazolones in the presence of sodium dodecyl sulfate in aqueous media
Wang, Wei,Wang, Shu-Xiang,Qin, Xin-Ying,Li, Ji-Tai
, p. 1263 - 1269 (2005)
The environmentally friendly condensation 3-methyl-1-phenyl-5-pyrazolone or 3-methyl-1H-5-pyrazolone with aromatic and aliphatic aldehydes was performed in water at refluxing temperature for 1 h using sodium dodecyl sulfate (SDS) as the surfactant catalyst (5 mol%), giving 4,4′-alkylmethylene-bis(3-methyl- 5-pyrazolones) in 78.3%-92.1% yields. Copyright Taylor & Francis, Inc.
PEG-SO3H as a new, highly efficient and homogeneous polymeric catalyst for the synthesis of Bis(indolyl)methanes and 4, 4'-(Arylmethylene)- bis(3-methyl-1-phenyl-1hpyrazol-5-ol)s in water
Hasaninejad,Shekouhy,Zare,Hoseini Ghattali,Golzar
experimental part, p. 411 - 423 (2012/06/18)
In this work, a green, simple and highly efficient procedure for the synthesis of bis(indolyl)methanes and 4, 4'-(arylmethylene)-bis(3-methyl-1- phenyl-1H-pyrazol-5-ol)s [as an important class of bis(pyrazolyl)methanes] is described. The condensation of i
Multicomponent reactions of 1,3-disubstituted 5-pyrazolones and formaldehyde in environmentally benign solvent systems and their variations with more fundamental substrates
Tan, Jia-Neng,Li, Minghao,Gu, Yanlong
experimental part, p. 908 - 914 (2010/09/07)
Many multicomponent reactions (MCRs) of 1,3-disubstituted 5-pyrazolones and formaldehyde were developed in environmentally benign solvent systems. Styrenes, vinylferrocene and 2-phenylindoles could easily react, under solvent-free conditions or in glycerol solvent, with 1,3-disubstituted 5-pyrazolones and paraformaldehyde in the absence of any catalyst to afford a variety of complex skeletons in moderate to excellent yields. Particularly, these MCRs are proved to be combinable with the synthesis of 1,3-disubstituted 5-pyrazolones from phenylhydrazines and β-ketone esters in glycerol or a carboxylic acid-functionalized ionic liquid, [MIm-CO2H]BF 4. Therefore, some two-step sequential reactions of phenylhydrazines, β-ketone esters, formaldehyde and styrenes or indoles were developed for the first time. All these MCRs were conducted in environmentally benign solvent systems that not only minimize generation of wastes but also simplify the work-up procedure.
