98395-65-4

Basic information

• Product Name: 2-(2-Nitrophenoxy)ethylamine Hydrochloride
• Synonyms: 2-(2-Nitrophenoxy)ethylamine, HCl;2-(2-Nitrophenoxy)ethanamine hydrochloride;2-(2-Nitrophenoxy)ethylamine Hydrochloride
• CAS NO: 98395-65-4
• Molecular Formula: C₈H₁₀N₂O₃*ClH
• Molecular Weight: 218.63754
• Mol File: 98395-65-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-Nitrophenoxy)ethylamine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Nitrophenoxy)ethylamine Hydrochloride(98395-65-4)
• EPA Substance Registry System: 2-(2-Nitrophenoxy)ethylamine Hydrochloride(98395-65-4)

Safety Data

• Hazardous Substances Data: 98395-65-4(Hazardous Substances Data)

Usage

General Description

2-(2-Nitrophenoxy)ethylamine Hydrochloride, also known as nitrophenolamine, is a chemical compound that consists of a nitrophenol group and an ethylamine group. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and agricultural chemicals. The hydrochloride form of this compound is a stable and water-soluble salt, making it easier to handle and store. It is important to handle this chemical with care as it can be toxic and harmful if ingested, inhaled, or in contact with skin. Additionally, it is important to adhere to the proper safety guidelines and regulations when working with this chemical in laboratory or industrial settings.

Upstream product

• 98395-64-3 N-(2-ortho-nitrophenoxyethyl)phthalimide 

Downstream Products

• 4926-55-0 2-[(2-nitrophenyl)amino]ethanol 
• 98395-66-5 8-nitro-3,4-dihydro-2H-1,4-benzoxazine 

Relevant articles and documents

Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines

The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.