98395-66-5

Basic information

• Product Name: 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE
• Synonyms: 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE;8-NITRO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE;8-nitro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride
• CAS NO: 98395-66-5
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 216.62166
• Mol File: 98395-66-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE(98395-66-5)
• EPA Substance Registry System: 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE(98395-66-5)

Safety Data

• Hazardous Substances Data: 98395-66-5(Hazardous Substances Data)

Usage

General Description

8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE is a chemical compound with the molecular formula C8H7N3O4Cl. It is a nitroaromatic compound that is used in various chemical and pharmaceutical applications. The hydrochloride salt form of this compound is often used as a pharmaceutical intermediate in the synthesis of various drugs and medications. It is also used as a reagent in organic synthesis, particularly in the preparation of heterocyclic compounds. Additionally, this compound has potential applications in the field of medicinal chemistry and drug discovery, where it is studied for its biological activity and potential therapeutic uses.

Upstream product

• 98395-64-3 N-(2-ortho-nitrophenoxyethyl)phthalimide 
• 98395-65-4 1-amino-2-(2-nitrophenoxy)ethane hydrochloride 

Relevant articles and documents

Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines

The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.