98395-66-5 Usage
Uses
Used in Pharmaceutical Industry:
8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its role in this industry is crucial for the development of new therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE is used as a reagent, particularly for the preparation of heterocyclic compounds. Its properties make it a valuable component in creating complex organic molecules.
Used in Medicinal Chemistry and Drug Discovery:
8-NITRO-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE HYDROCHLORIDE is utilized in medicinal chemistry and drug discovery for studying its biological activity. Researchers investigate its potential therapeutic uses, which can lead to the development of new treatments and medications.
Check Digit Verification of cas no
The CAS Registry Mumber 98395-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,3,9 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 98395-66:
(7*9)+(6*8)+(5*3)+(4*9)+(3*5)+(2*6)+(1*6)=195
195 % 10 = 5
So 98395-66-5 is a valid CAS Registry Number.
98395-66-5Relevant academic research and scientific papers
Regioselectivity of Photochemical and Thermal Smiles Rearrangements and Related Reactions of β-(Nitrophenoxy)ethylamines
Wubbels, Gene G.,Halverson, Ann M.,Oxman, Joe D.,Bruyn, Van H. De
, p. 4499 - 4504 (2007/10/02)
The ortho, meta, and para isomers of β-(nitrophenoxy)ethylamine (1, 2, and 3, respectively) have been synthesized as hydrochloride salts.The corresponding ortho, meta, and para isomer of β-(nitrophenoxy)ethyl alcohol (4, 5, or 6, respectively), the Smiles rearrangement product, is formed cleanly in alkaline water by a thermal reaction from 1 or 3 and by a photochemical reaction from the triplet state of 2.Photolysis of 1 or 3 does not cause Smiles rearrangement; photoproducts recovered from 1 and 3 show that β-amino group in both cases bonds at the ring carbon atom adjacent to the side chain and meta to the nitro group.The contrast of these results with those reported for photo-Smiles rearrangements of similar systems containing NHPh as the attacking nucleophile and for intermolecular aromatic photosubstitution by alkylamines is discussed.The results support the recently proposed "energy gap" model for predicting regioseelctivity in heterolytic nucleophilic aromatic photosubstitution.
