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Usage

Uses

Used in Pharmaceutical Industry:
Pyridine, 4-chloro-2-ethenyl(9CI) is used as a key building block for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of medicinal compounds with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, Pyridine, 4-chloro-2-ethenyl(9CI) serves as a crucial intermediate in the development of pesticides and other agricultural chemicals, contributing to enhanced crop protection and yield.
Used in Organic Synthesis Research and Development:
Pyridine, 4-chloro-2-ethenyl(9CI) is utilized as a reagent or catalyst in organic synthesis within research and development settings. Its presence can facilitate or improve the efficiency of certain chemical reactions, leading to the production of desired organic compounds.
Used in Industrial Chemical Production:
Pyridine, 4-chloro-2-ethenyl(9CI) also plays a role as an intermediate in the manufacturing process of various industrial chemicals, highlighting its versatility and importance in different chemical processes.

Upstream product

• 121638-26-4 (+/-)-4-chloro-2-(1-hydroxyethyl)pyridine 
• 626-61-9 4-Chloropyridine 
• 18880-10-9 4-chloro-2-ethylpyridine N-oxide 
• 38594-62-6 2-ethyl-4-nitropyridine N-oxide 
• 4833-24-3 2-ethylpyridine 1-oxide 
• 100-71-0 2-Ethylpyridine 

Relevant academic research and scientific papers

Tuning copper-dioxygen reactivity and exogenous substrate oxidations via alterations in ligand electronics

Copper(I)-dioxygen adducts are important in biological and industrial processes. For the first time we explore the relationship between ligand electronics, CuI-O2 adduct formation and exogenous substrate reactivity. The copper(I) complexes [CuI(R-MePY2)]+ (1R, where R = Cl, H, MeO, Me2N) were prepared; where R-MePY2 are 4-pyridyl substituted bis[2-(2-pyridyl)ethyl]methylamine chelates. Both the redox potential of 1R (ranging from E 1/2 = -270 mV for 1Cl to -440 mV for 1MeN vs FeCp2/FeCp2+) and νCO of the CO adducts of 1R (ranging from 2093 cm-1 for 1Cl-CO to 2075 cm-1 for 1Me2N-CO) display modest but expected systematic shifts. Dioxygen readily reacts with 1H, 1MeO, and 1Me2N, forming the side-on peroxo-CuII2 complexes [{CuII(R-MePY2)}2(O2)]2+ (2R, also containing some bis-μ-oxo-CuIII2 isomer), but there is no reaction with 1Cl. Stopped-flow studies in dichloromethane show that the formation of 2Me2N from dioxygen and 1Me2N proceeds with a k = 8.2(6) × 104 M-2 s-1 (183 K, ?H- -20.3(6) KJ mol-1,?S=-219(3) J mol -1 K-1 Solutions of 2 R readily oxidize exogenous substrates (9,10- dihydroanthracene → N- methlaniline and formaldehyde, benzyl alcohol→ benzaldehyde, benzhydrol→ benzophenone, and methanol→ formaldehde), forming the bis -μ-hydroxo-Cu II2 complexes [{CuII(R-MePY2)(OH}2]) 2+(3R) Product yields increase as the R- group is made more electron-donating, and in some cases are quantitative with 2Me2N Pseudo-first-order rate constants for THF and methanol the strongest ligand donor (i.e., R=Me 2N). For THF oxidation to THF-OH a nearly 1500-fold increase in reaction rate is observed (kobs=2 (1)×10-5 S-1 for 2H to 3(1)× S-1 for 2Me2N), while methanol oxidation to formaldehyde exhibits an 2000- fold increase ( K obs= 5(1)×10-5 S-1 for 2H to 1(1)×10-1 S-1 for 2Me2N). Copyright